Abstract
Two main problems will be discussed: the first one is concerned with the mechanisms involved in the reciprocal regulation of the two nigrostriatal dopaminergic (DA) pathways. I will describe and summarize experiments which reveal the role of DA released from dendrites in this phenomenon. The second problem is related to some specific properties of the mesocortico-prefrontal DA neurons. Particularly, I intend to show that these neurons are distinct from those of the mesolimbic DA system which innervate subcortical structures and also originate from the ventro-tegmental area (VTA). The role of the mesocortico-prefrontal DA neurons in the regulation of DA transmission in subcortical structures through cortical efferent pathways will also be briefly discussed.
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Glowinski, J. (1982). In Vivo Regulation of Nigro-striatal and Mesocortico-prefrontal Dopaminergic Neurons. In: Bradford, H.F. (eds) Neurotransmitter Interaction and Compartmentation. NATO Advanced Study Institutes Series, vol 48. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1140-9_15
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DOI: https://doi.org/10.1007/978-1-4684-1140-9_15
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