Abstract
The history of melatonin starts in 1917, with the discovery that mammalian pineal gland extracts have the ability to lighten amphibian skin.14 About 40 years later, the skin-lightening constituent of the pineal gland, melatonin, was isolated and chemically identified as N-acetyl-5-methoxytryptamine by Lerner et al. 13
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Reppert, S.M., Klein, D.C., Perlow, M.J. (1980). Cerebrospinal Fluid Melatonin. In: Wood, J.H. (eds) Neurobiology of Cerebrospinal Fluid 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1039-6_40
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DOI: https://doi.org/10.1007/978-1-4684-1039-6_40
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