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Neurobiology of Cerebrospinal Fluid 1 pp 237–257Cite as

Seizure-Induced Metabolic Alterations in Human Cerebrospinal Fluid

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Abstract

The severe changes in systemic and cerebral metabolism associated with generalized tonic-clonic seizures have been a concern of physicians since the graphic description by Lucretius56 portraying a seizure victim:

Oft too some wretch, before our startled sight Struck as with lightning, by some keen disease Drops sudden: —by the dread attack o’erpowered He foams, he groans, he trembles, and he faints; Now rigid, now convulsed, his laboring lungs Heave quick, and quivers each exhausted limb, Spread through the frame, so deep the dire disease Perturbs his spirit: as the briny man Foams through each wave beneath the tempest’s ire

But when, at length, the morbid cause declines, And the fermenting humors from the heart Flow back—with staggering foot the man first treads Led gradual on to intellect and strength.

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Authors and Affiliations

  1. Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA

    Benjamin Rix Brooks M.D.

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  1. Benjamin Rix Brooks M.D.
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Editors and Affiliations

  1. Division of Neurosurgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, 19104, USA

    James H. Wood M.D. (Consultant) (Consultant)

  2. Pediatric Oncology Branch, National Cancer Institute National National Institutes of Health, Bethesda, Maryland, 20205, USA

    James H. Wood M.D. (Consultant) (Consultant)

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© 1980 Plenum Press, New York

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Brooks, B.R. (1980). Seizure-Induced Metabolic Alterations in Human Cerebrospinal Fluid. In: Wood, J.H. (eds) Neurobiology of Cerebrospinal Fluid 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1039-6_18

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  • DOI: https://doi.org/10.1007/978-1-4684-1039-6_18

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