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New Polypeptides in Measles Virus Infected Vero Cells

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Humoral Immunity in Neurological Diseases

Part of the book series: NATO ASI Series ((NSSA,volume 24))

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Abstract

The polypeptide composition of measles yirus and the synthesis of virus-specific proteins in CV-1 cells have been extensively analyzed by polyacrylamide gel electrophoresis (l, 2, 3, 4, 5). The different protein patterns of “purified measles virus” reveal similarities but also large differences. Using several previously described methods ve failed to prepare measles virus free of cellular proteins (cf.3). The significance of “purified measles virus preparations” must therefore be questioned. Pulse experiments with different cell lines (Vero, BSC-1, HEp-2, Hel) and two different measles virus strains (Edmonston A and B) result in the detection of up to 9 presiomable virus specific polypeptides with a MW between 90.000 and 30.000 daltons. According to their MS we find: p8l, p73, p67 p62, p58, p51, p43, p41 and P37.

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References

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Author information

Authors and Affiliations

  1. Department Microbiology, U.I.A, Wilrijk, Belgium

    D. A. Vanden Berghe & G. Huybreghts

Authors
  1. D. A. Vanden Berghe
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  2. G. Huybreghts
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Editor information

Editors and Affiliations

  1. Universitaire Instelling Antwerpen, Neurochemie Wilrijk, Belgium

    D. Karcher  & A. Lowenthal  & 

  2. Vrije Universiteit Brussel, St. Genesius-Rode, Belgium

    A. D. Strosberg

  3. Université Paris VII, Paris, France

    A. D. Strosberg

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© 1979 Plenum Press, New York

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Berghe, D.A.V., Huybreghts, G. (1979). New Polypeptides in Measles Virus Infected Vero Cells. In: Karcher, D., Lowenthal, A., Strosberg, A.D. (eds) Humoral Immunity in Neurological Diseases. NATO ASI Series, vol 24. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1003-7_46

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  • DOI: https://doi.org/10.1007/978-1-4684-1003-7_46

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1005-1

  • Online ISBN: 978-1-4684-1003-7

  • eBook Packages: Springer Book Archive

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