Abstract
In the past few years a number of studies have been conducted on possible altered immune responses to viruses in patients with multiple sclerosis (MS). Several groups, including our own, have found slightly increased measles antibody levels in MS patients (1, 2). Recently, altered cellular immune responses to measles have been reported (5). Other studies have suggested the association of measles and an unidentified agent with MS (3, 4, 5, 6, 7, 8).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Brody, J., Sever, J.L., Edgar, A., and McNew, J., 1972, Measles antibody titers of multiple; sclerosis patients and their siblings, Neurology 22:492.
Adams, J., and Imagawa, D., 1962, Measles antibodies in multiple sclerosis, Proc. Soc. Exp. Biol. Med. 111:562.
Carp, R.I., Licursi, P.C., Merz, P.A., and Merz, G.S., 1972, Decrease percentage of polymorphonucelar neutrophils in mouse peripheral blood after inoculation with material from multiple sclerosis patients, J. Exper. Med. 136:618.
Carp, R.I., Licursi, P.C., and Merz, G.S., 1975, Multiple sclerosis induced reduction in the yield of a mouse cell line, Infect. Immun. 11:737.
Levy, N.L., Auerbach, P.S., and Hayes, E.C., 1976, A blood test for multiple sclerosis based on the adherence of lymphocytes to measles infected cells, N. Engl. J. Med. 294:1423.
Pertschuk, L.P., Cook, A.W., and Gupta, J., 1976, Measles antigen in multiple sclerosis: Identification in the jejunum by immunofluorescence. Life Sci. 19: l603.
Koldovsky, U., Koldovsky, P., Henle, G., Henle, W., Ackermann, R., and Haasse, G., 1975, Multiple sclerosis associated agent: transmission to animals and some properties of the agent. Infect. Immun. 12:1355.
Henle, G., Koldovsky, U., Koldovsky, P., Henle, W., Ackerman, R., and Haasse, G., 1976, Multiple sclerosis associated agent. Neutralization of the agent by human sera, Infect. Immun. 12:1367.
Fuccillo, D.A., Moder, F.L., Catalane, L.W., Vincent, M.M., and Sever, J.L., 1970, Herpesvirus hominis type I and II. A specific micro-indirect hemagglutination test, Proc. Soc. Biol. Med. 133:735.
Kihler, R., and ter Meulen, V., 1975, Antibody-mediated cytotoxicity after measles virus infection, J. Immunol. 114:93.
Steele, R.W., Hensen, S.A., Vincent, M.M., Fuccillo, D.A., and Bellanti, J.H., 1973, A 51Cr microassay technique for cell-mediated immimity to viruses, J. Immunol. 110:1502.
Utermohlen, V., and Zabriskie, J.B., 1973, A suppression of cell-mediated immunity in patients -with multiple sclerosis, J. Exp. Med. 138:1591.
Steele, R.W., Fuccillo, D.A., Hensen, S.A., Vincent, M.M., and Bellanti, J.A., 1976, Specific inhibitory factors of cellular immunity in children with subacute sclerosing panencephalitis, J. Pediatr. 88:56.
Prevost, J., Orr, T.W., and Pearson, G.R., 1975, Augmentation of lymphocyte cytotoxicity by antibody to Herpesvirus saimiri associated antigens, Proc. Nat. Acad. Sci. 72: l671.
Kurtzke, J.F., Kurland, L.T., Goldberg, I.D., and Choi, N.W., 1973, Multiple Sclerosis: Kurland, L.T., Kurtzke, J.F., and Goldberg, I.D. (eds.) Epidemiology, of Neurologic and Sense Organ Disorders, Harvard University Press, Cambridge, Mass.
Myers, L.W., Ellison, G.W., Feurster, M.E., Teraski, P., and Opetz, G., 1976, HLA and the immune response to measles in multiple sclerosis. Neurology 26:54.
Winchester, R.J., Ebers, G., Fu, S.M., Espinosa, L., Zabriskie, J., and Kunkel, H.G., 1975, B-cell alloantigens Ag 7a in multiple sclerosis. The Lancet ii:814.
Jersild, C., Fog, T., Hansen, G.S., Thomsen, M., Svejgoard, A., and Dupont, B., 1973, Histocompatibility determinants in multiple sclerosis with special reference to clinical course. The Lancet ii:1221.
Fuccillo, D.A., Abela, J.E., Traub, R.G., Gillespie, M.M., Beadle, E.L., and Sever, J.L., 1975, Cellular immunity in patients with multiple sclerosis. The Lancet i:980.
Opelz, G., Terasaki, P., Myers, L., Ellison, G., Ebers, G., Zabriskie, J., Kempe, H., Sibley, W., and Sever, J., 1976, HLA-D locus typing in 350 patients with multiple sclerosis. In The First International Symposium on the HLA and Disease, Paris, June 1976, ISERM, Paris.
Alter, M.M., Harshe, M., Anderson, V.E., Emme, L., and Yunis, E.J., 1976, Genetic association of multiple sclerosis and HLA-A determinants, Neurology 26:31.
Hones, J., Herva, E., Reimanen, M., Panelius, M., Meurman, O., Arstila, P., and Tiilikaines, A., 1977, HLA antigens and antibody responses to measles and rubella viruses in multiple sclerosis. Acta. Neurol. Scand. 55:299.
Paty, D., Furesz, J., Boucher, W., Rand, C.G., and Stiller, C.R., 1976, Measles antibodies as related to HLA types in multiple sclerosis, Neurology 26:651.
Offner, H., Konat, G., and Clausen, J., 1977, A blood test for multiple sclerosis, N. Eng. J. Med. 296:451.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1979 Plenum Press, New York
About this chapter
Cite this chapter
Madden, D.L., Wallen, W.C., Sever, J.L. (1979). Cellular Immunology in Multiple Sclerosis Response to Several Viruses. In: Karcher, D., Lowenthal, A., Strosberg, A.D. (eds) Humoral Immunity in Neurological Diseases. NATO ASI Series, vol 24. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1003-7_3
Download citation
DOI: https://doi.org/10.1007/978-1-4684-1003-7_3
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-1005-1
Online ISBN: 978-1-4684-1003-7
eBook Packages: Springer Book Archive