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The Functional Roles of Metals in Metalloenzymes

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Book cover Protein-Metal Interactions

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 48))

Abstract

There is now widespread appreciation for the fact that overall and local changes in protein conformation are critical to the mechanism of enzymatic catalysis. Yet, it has been difficult to document the occurrence and judge the significance of such changes, since methods for the analysis of protein structure often require conditions which cannot be compared easily and directly with those designed for determining function. This is true even while the number, resolving power and sophistication of suitable approaches has increased rapidly.

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Author information

Authors and Affiliations

  1. Biophysics Research Laboratory, Department of Biological Chemistry, Harvard Medical School, Boston, Ma., 02115, USA

    J. F. Riordan & B. L. Vallee

Authors
  1. J. F. Riordan
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  2. B. L. Vallee
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Editor information

Editors and Affiliations

  1. U. S. Department of Agriculture, Western Regional Research Laboratory, Agricultural Research Service, Berkeley, California, USA

    Mendel Friedman

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© 1974 Plenum Press, New York

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Riordan, J.F., Vallee, B.L. (1974). The Functional Roles of Metals in Metalloenzymes. In: Friedman, M. (eds) Protein-Metal Interactions. Advances in Experimental Medicine and Biology, vol 48. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0943-7_2

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  • DOI: https://doi.org/10.1007/978-1-4684-0943-7_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0945-1

  • Online ISBN: 978-1-4684-0943-7

  • eBook Packages: Springer Book Archive

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