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Effects of Alcohol on Aging in the Nervous System

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Part of the book series: Advances in Behavioral Biology ((ABBI,volume 16))

Abstract

Alcoholism is one of the major health problems of the world. In the United States, it is believed that between 6 to 8 million adults of the total population of 220 million may be addicted to alcohol. It is generally overlooked that in terms of addiction, alcohol is of far greater importance than all of the other drugs combined (Rubin and Lieber, 1971). Alcoholism occurs as a consequence of chronic drinking and some form of predisposition, either psychological, biochemical, or genetic in nature. Recently, it has been shown that alcoholism is a form of drug addiction according to pharmacological criteria of tolerance and dependence (Mendelson and Mello, 1969). Various genetic and other psychosocial factors, such as sex, age, education, occupation, income and religion may all play an important role in the drinking habits of a population. According to one survey (Cahalan and Cisin, 1968), older people generally appear to drink less than younger people. However, senescence in some individuals is often associated with many adaptational and behavioral problems such as depression and anxiety brought on by financial insecurity, disability, or death of a family member (Busse and Pfeiffer, 1969). Such conditions may frequently lead to excessive drinking in some members of an older population.

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References

  • Armstrong, C. M. and Binstock, L. J. Gen. Physiol., 48: 265, 1964.

    Article  CAS  Google Scholar 

  • Bender, A. D. J. Am. Geriat. Soc., 18: 220, 1970.

    CAS  Google Scholar 

  • Bishayee, S. and Balasubramanian, A. S. J. Neurochem., 18: 909, 1971.

    Article  CAS  Google Scholar 

  • Busse, E. W. and Pfeiffer, E. In: Behavior and Adaptations in Late Life (Eds. Busse, E. W. and Pfeiffer, E. ). Boston, Little Brown and Co., 1969.

    Google Scholar 

  • Cahalan, D. and Cisin, I. H. Quart. J. Stud. Ale., 29: 130, 1968.

    Google Scholar 

  • Comfort, A. Lancet, ii:1325, 1966.

    Article  Google Scholar 

  • Corrodi, H., Fuxe, K. and Hokfelt, T. J. Pharm. Pharmacol., 18: 821, 1966.

    Article  CAS  Google Scholar 

  • Costa, E. and Neff, N. H. In: Handbook of Neurochemistry, Vol. 4 (Ed. Lajtha, A. ). New York, Plenum Press, 1970.

    Google Scholar 

  • Eidelberg, E. and Wooley, D. F. Arch. Int. Pharmacodyn., 185: 388, 1970.

    CAS  Google Scholar 

  • Freund, G. and Walker, D. W. Life Sci., 10: 1343, 1971.

    Article  CAS  Google Scholar 

  • Frolkis, V. V. Triangle, 8: 322, 1969.

    Google Scholar 

  • Gaitz, C. M. (Ed.) In: Aging and the Brain. New York, Plenum Press, 1972.

    Google Scholar 

  • Gursey, D. and Olson, R. E. Proc. Soc. Exp. Biol. Med., 104: 280, 1960.

    CAS  Google Scholar 

  • Hsu, L. L., Samorajski, T., Ordy, J. M., Bose, H. and Curtis, H. J. J. Neurochem., 18: 1719, 1971.

    Article  CAS  Google Scholar 

  • Isbell, H., Fräser, H. F., Wilker, A., Bellville, R. E. and Eisenman, A. J. Quart. J. Stud, Alc., 16: 1, 1955.

    CAS  Google Scholar 

  • Israel, Y., Kalant, H. and Lanfer, I. Blochem. Pharmacol., 14: 1803, 1965.

    Article  CAS  Google Scholar 

  • Israel, Y., Kalant, H. and LeBlanc, A. E. Biochem. J., 100: 27, 1966.

    CAS  Google Scholar 

  • Israel, Y., Kalant, H., LeBlanc, A. E., Bernstein, J. C. and Salazar, I. J. Pharmacol. Exp. Thera., 174: 330, 1970.

    CAS  Google Scholar 

  • Israel, Y. and Salazar, I. Arch. Biochem. Biophys., 122: 310, 1967.

    Article  CAS  Google Scholar 

  • Israel, Y. Quart. J. Stud. Alc., 31: 293, 1970.

    CAS  Google Scholar 

  • Israel-Jacord, Y. and Kalant, H. J. Cell. Comp. Physiol., 65: 127, 1966.

    Article  Google Scholar 

  • Kalant, H. In: Alcohols and Derivatives, Vol. 1 (Ed. Tremoliers, J. ). Oxford, Pergamon Press, 1970.

    Google Scholar 

  • Kariyama, K. Rauscher, G. E. and Sze, P. Y. Brain Res., 26: 450, 1971.

    Google Scholar 

  • Korenchevsky, V. In: Physiological and Pathological Aging. New York, Hafner Publishing Co., 1961.

    Google Scholar 

  • Leevy, C. M., Tanribili, A. K. and Smith, F. In: The Biology of Alcoholism, Vol. 1 (Eds. Kissin, B. and Begleiter, H. ). New York, Plenum Press, 1971.

    Google Scholar 

  • Lehmann, H. E. In: Aging and the Brain (Ed. Gaitz, C. M. ). New York, Plenum Press, 1972.

    Google Scholar 

  • Lemere, F. Am. Psychiat., 113: 361, 1956.

    CAS  Google Scholar 

  • Mendelson, J. H. and Mello, N. K. In: Psychochemical Research in Man (Eds. Mendell, A. J. and Mendell, M. P. ). New York, Academic Press, 1969.

    Google Scholar 

  • Molinoff, P. B. and Axelrod, J. Ann. Rev. Biochem., 40: 465, 1971.

    Article  CAS  Google Scholar 

  • Moore, J. W., Albricht, W. and Takata, M. J. Gen. Physiol., 48: 279, 1964.

    Article  CAS  Google Scholar 

  • Portig, P. J. and Vogt, M. J. Physiol (London), 204: 687, 1969.

    CAS  Google Scholar 

  • Post, M. E., Samorajski, T. and Sun, A. Y. Abstract, 4th Interna-tional Meeting of the International Society for Neurochemistry, Tokyo, Japan, 1973.

    Google Scholar 

  • Rubin, E. and Lieber, C. S. Science, 172: 1097, 1971.

    CAS  Google Scholar 

  • Samaha, F. J.,J. Neurochem., 14: 333, 1967.

    Article  PubMed  CAS  Google Scholar 

  • Samorajski, T. and Ordy, J. M. In: Aging and the Brain (Ed. Gaitz, C. M. ). New York, Plenum Press, 1972.

    Google Scholar 

  • Samorajski, T., Rolsten, C. and Ordy, J. M. Geront., 26: 168, 1971.

    Article  CAS  Google Scholar 

  • Skou, J. C. Physiol. Rev., 45: 596, 1965.

    CAS  Google Scholar 

  • Sun, A. Y. Biochim. Biophys. Acta, 266: 350, 1972.

    Article  CAS  Google Scholar 

  • Sun, A. Y. Abstract, 4th International Meeting of the Interna-tional Society for Neurochemistry, Tokyo, Japan, 1973b.

    Google Scholar 

  • Sun, A. Y. Abstract, 3rd Annual Meeting of the Society for Neuro- science, San Diego, California, 1973c.

    Google Scholar 

  • Sun, A. Y. and Samorajski, T. J. Neurochem., 17: 1365, 1970.

    Article  CAS  Google Scholar 

  • Sun, A. Y., Sun, G. Y. and Samorajski, T. J. Neurochem., 18: 1711, 1971.

    Article  CAS  Google Scholar 

  • Sun, G. Y. and Samorajski, T. Biochim. Biophys. Acta, 316: 19–27, 1973.

    Article  PubMed  CAS  Google Scholar 

  • Sun, G. Y. and Sun, A. Y. Biochim. Biophys. Acta., 280: 306, 1972.

    Article  CAS  Google Scholar 

  • Wallgren, H. Psychosomat. Med., 28: 431, 1966.

    CAS  Google Scholar 

  • Wiberg, G. S., Trenholm, H. L. and Coldwell, B. B. Toxicol. Appl. Pharmacol., 16: 718, 1970.

    Article  CAS  Google Scholar 

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© 1975 Plenum Press, New York

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Sun, A.Y., Ordy, J.M., Samorajski, T. (1975). Effects of Alcohol on Aging in the Nervous System. In: Ordy, J.M., Brizzee, K.R. (eds) Neurobiology of Aging. Advances in Behavioral Biology, vol 16. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0925-3_22

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  • DOI: https://doi.org/10.1007/978-1-4684-0925-3_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0927-7

  • Online ISBN: 978-1-4684-0925-3

  • eBook Packages: Springer Book Archive

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