Hormonal Regulation of Ovalbumin Synthesis in Chick Oviduct

  • R. T. Schimke
  • R. Palacios
  • R. D. Palmiter
  • R. E. Rhoads
Part of the Basic Life Sciences book series


Estrogens and progesterone regulate the differentiation and function of chick oviduct (1–4). Our attention has been focused on hormonal regulation of ovalbumin synthesis, since this single polypeptide comprises 50–60% of the protein synthesized in the fully differentiated oviduct. This feature allows potentially for isolation of the molecular elements involved in specific protein synthesis, including specific polysomes, mRNA, and genes, and an analysis of various regulatory steps between transcription and translation of specific mRNAs, as affected by developmental and hormonal variables.


Hormonal Regulation Rabbit Reticulocyte Lysate Estradiol Benzoate Primary Stimulation Reaction Misture 
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Copyright information

© Plenum Press, New York 1973

Authors and Affiliations

  • R. T. Schimke
    • 1
  • R. Palacios
    • 1
  • R. D. Palmiter
    • 1
  • R. E. Rhoads
    • 1
  1. 1.Department of PharmacologyStanford University School of MedicineStanfordUSA

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