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DNA Synthesis pp 517–558Cite as

Structure and Catalytic Properties of Human DNA Polymerases α and β

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Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 17))

Abstract

In this paper we shall describe some of our recent studies on the structure and catalytic properties of DNA polymerases a and 8 (1) that we have purified from cultured human KB cells and from adult human livers. The principal topics of discussion will be the definition of the polypeptide composition of near homogeneous KB cell DNA polymerase a, the problem of the intracellular localization of polymerase a, and the results of our initial studies on the specific in Vitro replication of human D-loop mitochondrial DNA (mtDNA) by near homogeneous human DNA polymerase

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Author information

Authors and Affiliations

  1. Laboratory of Experimental Oncology, Department of Pathology, Stanford University School of Medicine, Stanford, California, 94305, USA

    David Korn, Duane C. Eichler, Paul A. Fisher & Teresa Shu-Fong Wang

Authors
  1. David Korn
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  2. Duane C. Eichler
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  3. Paul A. Fisher
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  4. Teresa Shu-Fong Wang
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Editor information

Editors and Affiliations

  1. Imperial Cancer Research Fund, London, England

    Ian Molineux

  2. University of Paris, Paris, France

    Masamichi Kohiyama

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© 1978 Plenum Press, New York

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Korn, D., Eichler, D.C., Fisher, P.A., Wang, T.SF. (1978). Structure and Catalytic Properties of Human DNA Polymerases α and β. In: Molineux, I., Kohiyama, M. (eds) DNA Synthesis. NATO Advanced Study Institutes Series, vol 17. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0844-7_39

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  • DOI: https://doi.org/10.1007/978-1-4684-0844-7_39

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0846-1

  • Online ISBN: 978-1-4684-0844-7

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