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Metals as Mutagens

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Inorganic and Nutritional Aspects of Cancer

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 91))

Summary

A number of metals are mutagenic in bacteria or phage. These include compounds of arsenic, chromium, copper, iron, manganese, molybdenum, platinum, and selenium. Compounds containing aluminum, antimony, arsenic, cadmium, copper, lead, mercury, nickel, and tellurium have been shown to induce chromosomal aberrations or abnormal cell divisions in animal or plant cells. Genetic evidence suggests that arsenic, chromium, and molybdenum compounds may influence the accuracy of DNA repair processes in microorganisms.

Mutagens: Compounds which induce well-characterized heritable phenotypic changes in genetically described viruses, cell lines, or organisms.

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Author information

Author notes

  1. C. Peter Flessel

    Present address: Department of Health, Biochemistry Group, Air and Industrial Hygiene Laboratory, State of California, 2151 Berkeley Way, Berkeley, California, USA

Authors and Affiliations

  1. Department of Biology, University of San Francisco, San Francisco, California, 94117, USA

    C. Peter Flessel

Authors
  1. C. Peter Flessel
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Editor information

Editors and Affiliations

  1. University of California at San Diego, La Jolla, California, USA

    G. N. Schrauzer

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© 1978 Plenum Press, New York

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Flessel, C.P. (1978). Metals as Mutagens. In: Schrauzer, G.N. (eds) Inorganic and Nutritional Aspects of Cancer. Advances in Experimental Medicine and Biology, vol 91. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0796-9_9

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  • DOI: https://doi.org/10.1007/978-1-4684-0796-9_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0798-3

  • Online ISBN: 978-1-4684-0796-9

  • eBook Packages: Springer Book Archive

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