Abstract
Experimental and theoretical methods can be two complementary arms in clinical research. Mathematical or geometrical models implemented on computers provide the means of testing new medical procedures, or evaluating the effects of surgery and drugs on patient recovery and functional limits. When sufficiently accurate physiological or structural models are available, it is preferable to perform ‘bloodless’ experiments on the computer models before attempting actual treatment. In clinical applications, predictions from model simulations can be used to explore new protocols for the evaluation of patients; if the models relate well with known anatomy and physiology, they can even be used to evaluate the function of selected central nervous system pathways, noninvasively. Examples of the potential role of computer models in medical research and practice are presented below, followed by an application in the study of the human vestibulo-ocular system.
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© 1991 Springer-Verlag New York Inc.
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Galiana, H.L. (1991). Using Computer Models. In: Troidl, H., et al. Principles and Practice of Research. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-0371-8_38
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DOI: https://doi.org/10.1007/978-1-4684-0371-8_38
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