Abstract
Over the last several years an increasing amount of research has implicated the importance of oxygen free radicals in the etiology of several diseases and pathological conditions. Proof of the importance of oxygen free radicals and the oxidative damage they initiate depends on methods that will unequivocally establish not only the presence of oxygen free radicals but a clear association of their formation with the induced oxidative damage and a clear-cut relationship with the induction or progression of the disease or pathological condition. This has been a difficult research area where newer methods have begun to yield results. This brief chapter has three aims: define the problems facing the experimentalist in this area, present basic concepts underlying newer methods available, and summarize recent results obtained on a model system. The results clearly add credence to the notion that oxygen free radicals and oxidative damage are etiological agents in the development of tissue injury caused by oxidative insults.
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© 1993 Springer Science+Business Media New York
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Floyd, R.A. (1993). In Vivo Detection of Oxygen Free Radical Species. In: Tarr, M., Samson, F. (eds) Oxygen Free Radicals in Tissue Damage. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4615-9840-4_5
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DOI: https://doi.org/10.1007/978-1-4615-9840-4_5
Publisher Name: Birkhäuser, Boston, MA
Print ISBN: 978-1-4615-9842-8
Online ISBN: 978-1-4615-9840-4
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