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Synthetic Pro-oxidants: Drugs, Pesticides and Other Environmental Pollutants

  • Chapter
Oxidative Stress and Antioxidant Defenses in Biology

Abstract

In recent years, a tremendous increase has occurred in our knowledge regarding the role of reactive oxygen species (ROS) in the toxicity of numerous xenobiotics and in the pathology of various disease states. The number of xenobiotics known to promote the formation of ROS has expanded greatly. Furthermore, oxidative stress is believed to be involved in the pathophysiology of aging, and various age-related diseases including cataracts, atherosclerosis, neoplastic diseases, diabetes, diabetic retinopathy, chronic inflammatory diseases of the gastrointestinal tract, aging of skin, diseases associated with cartilage, Alzheimer’s disease, and other neurological disorders including Down’s syndrome (see also chapter 2) (Emerit and Chance, 1992).

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    Sami Ahmad

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Stohs, S.J. (1995). Synthetic Pro-oxidants: Drugs, Pesticides and Other Environmental Pollutants. In: Ahmad, S. (eds) Oxidative Stress and Antioxidant Defenses in Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9689-9_4

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