Abstract
In most mammals the mechanism contributing to the regulation of glucose metabolism does not seem to be fully developed during suckling. Glucose infusion to the suckling rat (1) is followed by a marked hyperglycemia concomitant to the persistence of hepatic glucose production. Moreover, glucose tolerance capacity during suckling, as determined by intragastric tolerance test, is lower in suckling than in weaned rats (2). Either hormonal or nutritional changes occurring during the suckling-to-weaning transition are likely to contribute to the full development of the metabolic capacities of the pups. In fact, in most mammals weaning corresponds to a change from a low-carbohydrate, high-fat diet (milk) to a high-carbohydrate, low-fat diet and the role of this nutritional transition on the appearance of the adult characteristics is not well understood.
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© 1990 Plenum Press, New York
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Issad, T., Pastor-Anglada, M., Coupé, C., Ferré, P., Girard, J. (1990). Glucose Metabolism and Insulin Sensitivity During Suckling Period in Rats. In: Cuezva, J.M., Pascual-Leone, A.M., Patel, M.S. (eds) Endocrine and Biochemical Development of the Fetus and Neonate. Reproductive Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9567-0_8
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DOI: https://doi.org/10.1007/978-1-4615-9567-0_8
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