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Effect of Physiological Changes in Cystathionase Activity on Amino Acid and Glutathione Metabolism in Rat Fetus

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Endocrine and Biochemical Development of the Fetus and Neonate

Part of the book series: Reproductive Biology ((RBIO))

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Abstract

The trans-sulphuration pathway serves to synthesize cysteine from methionine. This pathway is important to ensure an adequate supply of cysteine and, indeed, if the flux through the pathway is decreased, cysteine becomes an essential amino acid. A key enzyme of the pathway is cystathionase, which catalyzes the cleavage of cystathionine to yield cysteine.

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Author information

Authors and Affiliations

  1. Departamento de Fisiología, Facultad de Medicina, 46010, Valencia, Spain

    José Viña, Esperanza Gasco, Federico V. Pallardo, Juan Sastre, José M. Estrela & Francisco Rodrigo

Authors
  1. José Viña
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  2. Esperanza Gasco
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  3. Federico V. Pallardo
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  4. Juan Sastre
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  5. José M. Estrela
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  6. Francisco Rodrigo
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Editor information

Editors and Affiliations

  1. Universidad Autonoma de Madrid, Madrid, Spain

    José M. Cuezva

  2. C.S.I.C. Universidad Complutense de Madrid, Madrid, Spain

    Ana M. Pascual-Leone

  3. Case Western Reserve University, Cleveland, Ohio, USA

    Mulchand S. Patel

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© 1990 Plenum Press, New York

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Viña, J., Gasco, E., Pallardo, F.V., Sastre, J., Estrela, J.M., Rodrigo, F. (1990). Effect of Physiological Changes in Cystathionase Activity on Amino Acid and Glutathione Metabolism in Rat Fetus. In: Cuezva, J.M., Pascual-Leone, A.M., Patel, M.S. (eds) Endocrine and Biochemical Development of the Fetus and Neonate. Reproductive Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9567-0_30

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  • DOI: https://doi.org/10.1007/978-1-4615-9567-0_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9569-4

  • Online ISBN: 978-1-4615-9567-0

  • eBook Packages: Springer Book Archive

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