Coupling of Hemodynamics to Diffusional Oxygen Mass Transport

  • K. Groebe
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 215)


Maximally working skeletal muscle exhibits one of the highest O 2 consumption rates observed in any tissue. In order to understand the mechanisms which bring about these enormous oxygen fluxes, two key questions have to be addressed:
  1. 1.

    How can diffusional fluxes of that magnitude from the red blood cell into the muscle fiber be achieved in spite of unfavourably long diffusion paths?

  2. 2.

    How is it possible that red cell transit times through the capillary bed are sufficiently long to discharge enough oxygen even though blood flow values are 25-fold compared to rest and the capillary bed is significantly de-recruited due to raised tissue pressures.



Transit Time Flow Path Functional Capillary Density Transit Time Distribution Discharge Hematocrit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • K. Groebe
    • 1
  1. 1.Dept. of Mechan. Engin.University of RochesterRochesterUSA

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