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Mechanisms of Stimulus—Response Coupling in Platelets pp 249–263Cite as

Protein Kinase C and Granule Release in Human Platelets

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 192))

Abstract

Upon activation at sites of vascular injury or in response to physiological stimuli, platelets undergo a number of biochemical changes associated with aggregation and release of various secretory granules by exocytosis. A number of proteins and biologically active substances such as thrombospondin, serotonin, ADP and PDGF are secreted.

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Author information

Authors and Affiliations

  1. Institut de Recherches Scientifiques sur le Cancer, BP n° 8, 9482, Villejuif Cedex, France

    M. Castagna, C. Pavoine & B. Mely

  2. Laboratoire de Chimie-Physiques des Macromolécules, CP 206/2, 1050, Bruxelles, Belgique

    R. Brasseur & J. M. Ruysschaert

  3. Unité INSERM 150, Hôpital Lariboisière, 6 rue Gay Patin Paris, Cedex 10, France

    R. Bredoux & S. Levy-Toledano

Authors
  1. M. Castagna
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  2. R. Brasseur
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  3. C. Pavoine
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  4. R. Bredoux
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  5. B. Mely
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  6. J. M. Ruysschaert
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  7. S. Levy-Toledano
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, Royal College of Surgeons, London, England

    J. Westwick

  2. Thrombosis Research Unit, King’s College School of Medicine and Dentistry, London, England

    M. F. Scully  & V. V. Kakkar  & 

  3. Department of Pharmacology, University of Glasgow, Glasgow, Scotland

    D. E. MacIntyre

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© 1985 Plenum Press, New York

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Castagna, M. et al. (1985). Protein Kinase C and Granule Release in Human Platelets. In: Westwick, J., Scully, M.F., MacIntyre, D.E., Kakkar, V.V. (eds) Mechanisms of Stimulus—Response Coupling in Platelets. Advances in Experimental Medicine and Biology, vol 192. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9442-0_18

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  • DOI: https://doi.org/10.1007/978-1-4615-9442-0_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9444-4

  • Online ISBN: 978-1-4615-9442-0

  • eBook Packages: Springer Book Archive

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