Isolated Thrombocytopenia in Homosexual Men — Longitudinal Follow-Up
One of the most clinically challenging, yet infrequently discussed, of the AIDS-associated syndromes is the problem of immune thrombocytopenic purpura (ITP). ITP is a diagnosis more frequently encountered in its acute form in children following viral infections and in its chronic presentation in middle-aged women. Morris et al published their account of auto-immune thrombocytopenic purpura in homosexual men in June 1984(1). Their manuscript described a cluster of ITP in 12 homosexual men with backgrounds similar to those recognized in patients with acquired immunodeficiency syndrome. Subsequently the problem has also been recognized in narcotics addicts and hemophiliacs without other manifestations of AIDS(2,3). To date, 32 homosexual men with isolated thrombocytopenia of immune origin have been evaluated in the AIDS Clinic at San Francisco General Hospital. Our experience with this group constitutes the basis of the following discussion.
KeywordsAcquire Immunodeficiency Syndrome Immune Thrombocytopenic Purpura Pneumocystis Carinii Pneumonia Elevated Erythrocyte Sedimentation Rate Prednisone Therapy
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