Photoreceptors pp 147-157 | Cite as

Some Basic Information About the Light Response of Frog Rods

  • P. B. Detwiler
Part of the NATO Asi Series book series (NSSA, volume 75)


The frog eye has been a standard preparation for vision research for more than a century. It has provided fundamental information about receptor photochemistry, the origin of the ERG and the properties of ganglion cells. In light of its history, it is surprising there is so little information about the cellular electrophysiology of the frog retina. This is particularly true of frog photoreceptors, which, to my knowledge, have been studied with intracellular electrodes on only one occasion (Toyoda, et al., 1970). As a result, there are several gaps in our understanding of their fundamental physiology. The aim of the present work was twofold: first to assess the practicality of using intracellular electrodes to study the frog retina and second, to answer some basic questions about the light response and spatial properties of frog rods.


Light Response Electrical Coupling Space Constant Rana Pipiens Dark Noise 
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  1. Bauman, Ch. (1977). Boll’s phenomenon. Vision Research 17, 1325–1327.CrossRefGoogle Scholar
  2. Baylor, D. A., and Fettipalce, R. (1975). Light path and photon capture in turtle photoreceptors, J. Physiol. 248: 433–464.PubMedGoogle Scholar
  3. Baylor, D.A., Fuortes, M. G. F., and O’Bryan, P. M. (1971). Receptive fields of single cones in the retina of the turtle, J. Physiol., 214, 265–294.PubMedGoogle Scholar
  4. Baylor, D.A., and Hodgkin, A. L. (1973). Detection and resolution of visual stimuli by turtle photoreceptors, J. Physiol., 234, 163–198.PubMedGoogle Scholar
  5. Brindley, G. S. (1953). The effects on colour vision of adaptation to very bright lights, J. Physiol., 122: 332–350.PubMedGoogle Scholar
  6. Cervetto, L., Pasino, E., and Torre, V. (1977). Electrical responses of rods in the retina of Bufo marinus, J. Physiol., 267, 17–51.PubMedGoogle Scholar
  7. Copenhagen, D. R., and Owen, W. G. (1976). Coupling between rod photoreceptors in a vertebrate retina. Nature, 260: 57–59.PubMedCrossRefGoogle Scholar
  8. Dartnall, H. J. A. (1972). Photosensitivity, in “Handbook of the sensory physiology” (Dartnall, H.J.A., ed.), pp. 122–145 Springer-Verlag, New York.Google Scholar
  9. DeMonasterio, F. M., Schein, S. J., and Mrane, E. P. (1981). Staining of blue-sensitive cones of the Macaque retina by a fluorescent dye. Science, 213, 1278–1271.PubMedCrossRefGoogle Scholar
  10. Denton, E. J., and Wyllie, J. H.(1955). Study of the photosensitive pigments in the pink and green rods of the frog, J. Physiol., 127, 81–89.PubMedGoogle Scholar
  11. Detwiler, P. B., and Hodgkin, A. L. (1979). Electrical coupling between cones in turtle retina, J. Physiol., 291, 75–100PubMedGoogle Scholar
  12. Detwiler, P. B., Hodgkin, A. L., and Maughton, P. A. (1978). A surprising property of electrical spread in the network of rods in the turtle retina. Nature, 274, 562–565.PubMedCrossRefGoogle Scholar
  13. Detwiler, P.B., Hodgkin, A. L., and Maughton, P. A. (1980). Temporal and spatial characteristics of the voltage response of rods in the retina of the snapping turtle, J. Physiol., 300, 213–250.PubMedGoogle Scholar
  14. Dowling, J.E., and Boycott, B.B. (1966). Organization of the primate retina: electron microscopy, Proc. Roy. Soc. B., 166, 80–111.CrossRefGoogle Scholar
  15. Fain, G. L. (1975). Quantum sensitivity of rods in the toad retina, Science, 18, 838–841.CrossRefGoogle Scholar
  16. Fain, G. L. (1976). Sensitivity of toad rods: dependence on wave length and background illumination, J. Physiol., 261, 71–101.PubMedGoogle Scholar
  17. Gold, G. H. (1979). Photoreceptor coupling in retina of the toad, Bufo marinus. II. Physiology, J. Neurophys., 42, 311–328.Google Scholar
  18. Lamb, T. D. (1976). Spatial properties of horizontal cell responses in the turtle retina, J. Physiol., 263, 239–255.PubMedGoogle Scholar
  19. Lamb, T. D., and Simon, E. J. (1976). The relation between intercellular coupling and electrical noise in turtle photoreceptors, J. Physiol., 263, 257–286.PubMedGoogle Scholar
  20. Leeper, H. F., Norman, R. A., and Copenhagen, D. R. (1978). Evidence for passive electronic interations in red rods of toad retina. Nature, 275, 234–236.PubMedCrossRefGoogle Scholar
  21. Liebman, P. A., and Entine, G. (1968). Visual pigments of frog and tadpole (Rana pipiens), Vision Res., 8, 761–775.PubMedCrossRefGoogle Scholar
  22. Nilsson, S. E. G. (1964a). An electron microscopic classification of the retinal receptors of the leopard frog, J. Ultrastruct. Res., 10, 390–416.PubMedCrossRefGoogle Scholar
  23. Nilsson, S. E. G. (1964b). Interreception contacts in the retina of the frog (Rana Pipiens), J. Ultrastruct. Res., 11, 147–165.PubMedCrossRefGoogle Scholar
  24. Osterberg, G. (1935). Topography of the layer of rods and cones in the human retina. Acta Ophtal. Suppl., 6, 1–103.Google Scholar
  25. Owen, W. G., and Torre, V. (1980). Ionic mechanism underlying the high-pass filtering of small signals by the rod network of the toad, Bufo marinus, J. Physiol., 308, 78 p.Google Scholar
  26. Schwartz, E. A.(1973). Responses of single rods in the retina of the turtle, J. Physiol., 232, 503–514.PubMedGoogle Scholar
  27. Schwartz, E. A.(1976). Electrical properties of the rod synctytium in the retina of the turtle, J. Physiol., 272, 217–246.Google Scholar
  28. Toyoda, J., Hashimoto, H., Anno, H., and Tomita, T. (1970). The rod response in the frog as studied by intracellular recording. Vision Res., 10, 1093–1100.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • P. B. Detwiler
    • 1
  1. 1.Department of Physiology and BiophysicsUniversity of WashingtonSeattleUSA

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