Abstract
Hybridoma cell lines producing monoclonal antibodies to mouse hepatitis virus strain A59 (MHV-A59) have been established by fusion of spleen cells of immunized mice with P3X63Ag8.653 mouse plasmacytoma cells. Culture fluids were screened for their ability to immunoprecipitate virus-specific proteins from 35S-methionine-labeled infected cells. Eleven clones were obtained which fell into three classes (Figure 1).
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Siddell, S.G., J. gen. Virol. 62:259–269 (1982).
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© 1984 Plenum Press, New York
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Koolen, M.J.M., Osterhaus, A.D.M.E., Siebelink, K.H.J., Horzinek, M.C., van der Zeijst, B.A.M. (1984). Monoclonal Antibodies to the Three Classes of Mouse Hepatitis Virus Strain A59 Proteins. In: Rottier, P.J.M., van der Zeijst, B.A.M., Spaan, W.J.M., Horzinek, M.C. (eds) Molecular Biology and Pathogenesis of Coronaviruses. Advances in Experimental Medicine and Biology, vol 173. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9373-7_10
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DOI: https://doi.org/10.1007/978-1-4615-9373-7_10
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