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Regulation of Protease Activity

  • Chapter
Proteases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 167))

Abstract

Proteases play a determinant role in many biological processes. In blood coagulation several enzymes are interrelated to form a cascade of reactions achieving amplification of the initial trigger reaction. Generally trigger mechanisms show a great diversity including negatively charged surfaces (Hageman Factor dependent pathways), antigen/antibody complexes (activation of the classical complement pathway), polysaccharides and lipopolysaccharides (alternate complement pathway) or specific enzymes such as urokinase or tissue activator in the case of fibrinolysis.

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Steinbuch, M. (1984). Regulation of Protease Activity. In: Hörl, W.H., Heidland, A. (eds) Proteases. Advances in Experimental Medicine and Biology, vol 167. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9355-3_2

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