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Tyrosine and 3,4-Dihydroxyphenyl-alanine Synthesis by Citrobacter freundii

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Enzyme Engineering

Abstract

Tyrosine phenol lyase catalyzes the splitting of L-tyrosine and L-3,4-dihydroxyphenyl-alanine (DOPA). The reversibility of both reactions allows this enzyme to be used for the synthesis of L-tyrosine and L-DOPA (1,2).

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References

  1. YAMADA, H., KUMAGAI, H., ENIE, H., MATSUI, H. & OKUMURA, S. Proc. IV IFS: Ferment. Technol. Today 445 (1972).

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  2. ENEI, H., MATSUI, H., YAMASHITA, K., OKUMURA, S. & YAMADA, H. Agr. Biol. Chem. 36: 1861 (1972).

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  3. OMELIANSKY, V. L. Ctrbl. Bakt. 2: 1903.

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  4. OMELIANSKY, V. L. “Bergey’s Manual of Determinative Bacteriology,” Williams and Wilkins Co., Baltimore (1974).

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  5. OGATA, K., YAMADA, H., ENEI, H.& OKUMURA, S., United States Patent 3,791,924 (1974)

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Author information

Authors and Affiliations

  1. Department of Microbiology, Moscow State University, Moscow, USSR

    N. S. Egorov, M. B. Koupletskaja & E. N. Kondratieva

Authors
  1. N. S. Egorov
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  2. M. B. Koupletskaja
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  3. E. N. Kondratieva
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Editor information

Editors and Affiliations

  1. Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Company, Osaka, Japan

    Ichiro Chibata

  2. Department of Industrial Chemistry, Faculty of Engineering, Kyoto University, Kyoto, Japan

    Saburo Fukui

  3. Department of Pharmacology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

    Lemuel B. Wingard Jr.

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© 1982 Plenum Press, New York

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Egorov, N.S., Koupletskaja, M.B., Kondratieva, E.N. (1982). Tyrosine and 3,4-Dihydroxyphenyl-alanine Synthesis by Citrobacter freundii . In: Chibata, I., Fukui, S., Wingard, L.B. (eds) Enzyme Engineering. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9290-7_32

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  • DOI: https://doi.org/10.1007/978-1-4615-9290-7_32

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9292-1

  • Online ISBN: 978-1-4615-9290-7

  • eBook Packages: Springer Book Archive

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