Abstract
The last 20 years have seen a veritable explosion in our knowledge about both animal and human tumors of the lymphoid and hemopoietic systems. Today, a bewildering amount of detailed information is available about the causes, varieties, and therapies of these tumors. The challenge for us all is to obtain a coherent overview of this forest of information, which will allow us to recognize individual trees as members of a particular grove, and to know the location of the empty tracts in which future generations may plant their trees.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Ades, E. W., Zwerner, R. K., Acton, R. T., and Balch, C. M., 1980, Isolation and partial characterization of the human homologue of Thy-1, J. Exp. Med. 151:400.
Argyris, B. F., 1978, Activation of suppressor cells by syngeneic tumor transplants in mice. Cancer Res. 38:1269.
Argyris, T. S., and Slaga, T. J., 1981, Promotion of carcinomas by repeated abrasion in initiated skin of mice, Cancer Res. 41:5193.
Baird, S. M., Beattie, G. M., Lannom, R. A., Lipsick, J. S., Jensen, F. C., and Kaplan, N. O., 1982, Induction of lymphoma in antigenically stimulated athymic mice, Cancer Res. 42:198.
Baltimore, D., 1980, “Viruses and Cancer,” Weinstein Lectureship, Tufts Medical School, April 15.
Bekesi, J. G., Roboz, J. P., Zimmerman, E., and Holland, J. F., 1976, Treatment of spontaneous leukemia in AKR mice with chemotherapy, immunotherapy, or interferon, Cancer Res. 36:631–639.
Benacerraf, B., 1981, Role of MHC gene products in immune regulation, Science 212:1229.
Benacerraf, B., and Germain, R. N., 1978, The immune response genes of the major histocompatibility complex, Immunol. Rev. 38:70.
Bloomfield, C. D., Gajl-Peczalska, K. J., Frizzera, G., Kersey, J. H., and Goldman, A. I., 1979, Clinical utility of surface markers combined with the Lukes-Collins histologic classification in adult lymphoma, N. Engl. J. Med. 301:512.
Boyd, A. W., Goding, J. W., and Schrader, J. W., 1981, The regulation of growth and differentiation of a murine B cell lymphoma. I. Lipopolysaccharide-induced differentiation, J. Immunol. 126:1261.
Broder, S., and Waldmann, T. A., 1978a, The suppressor-cell network in cancer, N. Engl. J. Med. 299:1281.
Broder, S., and Waldmann, T. A., 1978b, The suppressor-cell network in cancer, N. Engl. J. Med. 299:1335.
Broder, S., Muul, L., and Waldmann, T. A., 1978, Suppressor cells in neoplastic disease, J. Natl. Cancer Inst. 61:5.
Burnet, F. M., 1970, Immunological Surveillance, Pergamon Press, Elmsford, N.Y.
Clapp, N. K., 1973, An Atlas of RF Mouse Pathology: Disease Description and Incidences, Atomic Energy Commission Report UC-48, Springfield, Va.
Davey, G. C., Currie, G. A., and Alexander, P., 1979, A serologically detected tumour-specific membrane antigen of murine lymphomas which is not the target for syngeneic graft rejection, Br. J. Cancer 40:168.
De Noronha, F., Schäfer, W., Essex, M., and Bolognesi, D. P., 1978, Influence of antisera to oncornavirus glycoprotein (gp71) on infections of cats with feline leukemia virus, Virology 85:617.
Dent, P. B., 1972, Immunodepression by oncogenic viruses, Prog. Med. Virol. 14:1.
DiStefano, J. F., Beck, G., Lane, B., and Zucker, S., 1982, Role of tumor cell membrane-bound serine proteases in tumor-induced target cytolysis, Cancer Res. 42:207.
Dunn, T. B., 1954, Normal and pathological anatomy of the reticular tissue in laboratory mice, J. Natl. Cancer Inst. 14:1281.
Dunn, T. B., 1963, Histology of some neoplasms and non-neoplastic lesions found in wild mice maintained under laboratory conditions, J. Natl. Cancer Inst. 31:873.
Essex, M., Klein, G., Snyder, S. P., and Harrold, J. B., 1971, Correlation between humoral antibody and regression of tumours induced by feline sarcoma virus, Nature (London) 233:195.
Essex, M., Grant, C. K., Sliski, S. M., and Hardy, W. D., Jr., 1979, Leukemia specific antigens: FOCMA and immune surveillance, in: Modern Trends in Leukemia III (N. Neth, R. C. Gallo, P.-H. Hofschneider, and K. Mannweiler, eds.), pp. 454–467, Springer-Verlag, Berlin.
Evans, R., and Alexander, P., 1970, Cooperation of immune lymphoid cells with macrophages in tumor immunity, Eur. J. Cancer 6:620.
Evans, R., and Alexander, P., 1976, Mechanisms of extracellular killing of nucleated mammaliancells by macrophages, in: Immunology of the Macrophage (D. S. Nelson, ed.), pp. 535–576, Academic Press, New York.
Feeney, M., Knapp, R. C., Greenberger, J. S., and Bast, R. C., Jr., 1981, Elimination of leukemic cells from rat bone marrow using antibody and complement, Cancer Res. 41:3331.
Fish, D. C., Gilden, R. V., Bare, R. M., Trimmer, R. M., and Huebner, R. J., 1979, Prevention of spontaneous leukemia in AKR mice by passive immunization and type specificity of this protection, J. Natl. Cancer Inst. 62:943.
Frei, E., III, 1972, Combination cancer therapy: Presidential address, Cancer Res. 32:2593.
Friedman, H., 1975a, Immunosuppression by murine leukemia viruses, in: Viruses and Immunity (C. Koprowski and H. Koprowski, eds.), pp. 17–47, Academic Press, New York.
Friedman, H. (ed.), 1975b, Thymus Factors in Immunity, Ann. N.Y. Acad. Sci. 249:1.
Friedman, H. (ed.), 1979, Conference on Subcellular Factors in Immunity, Ann. N.Y. Acad. Sci. 332:1.
Furth, J., 1946, Prolongation of life with prevention of leukemia by thymectomy in mice, J. Gerontol. 1:46.
Furth, J., Okano, H., and Kunii, A., 1964, Role of the thymus in leukemogenesis, in: The Thymus in Immunobiology (R. A. Good and A. E. Gabrielson, eds.), pp. 595–622, Harper & Row, New York.
Geering, C., Old, L. J., and Boyse, E. A., 1966, Antigens of leukemias induced by naturally occurring murine leukemia virus: Their relation to antigens of Gross virus and other murine leukemia viruses, J. Exp. Med. 124:753.
George, S. L., Aur, R. J. A., Mauer, A. M., and Simone, J. V., 1979, A reappraisal of the results of stopping therapy in childhood leukemia, N. Engl. J. Med. 300:269.
Gershwin, M. E., Castles, J. J., Ahmed, A., and Makishima, R., 1978, The influence of α-fetoprotein on Moloney sarcoma virus oncogenesis: Evidence for generation of antigen nonspecific suppressor T cells, J. Immunol. 121:2292.
Goldfeder, A., Kauffman, S. L., and Ghosh, A. K., 1966, Carcinogenesis in naturally tumour-resistant mice: X-Irradiation versus urethane as a carcinogenic agent, Br. J. Cancer 20:361.
Goldstein, G., Scheid, M. P., Boyse, E. A., Schlesinger, D. H., and Wauwe, J. V., 1979. A synthetic pentapeptide with biological activity characteristic of the thymic hormone thymopoietin, Science 204:1309.
Good, R. A., 1975, Clinical implications of the data base concerning the tumor-host relationship, in: Immunobiology of the Tumor-Host Relationship (R. T. Smith and M. Landy, eds.), pp. 277–301, Academic Press, New York.
Greaves, M. F., 1981, Monoclonal antibodies as probes for leukaemic heterogeneity and haemopoietic differentiation, in: Leukemia Markers (W. Knapp, ed.), pp. 19–32, Academic Press, New York.
Greene, M. I., Dorf, M. E., Pierres, M., and Benacerraf, B., 1977, Reduction of syngeneic tumor growth by an anti-I-J alloantiserum, Proc. Natl. Acad. Sci. USA 74:5118.
Gross, L., 1951, Pathogenic properties, and “vertical transmission” of the mouse leukemia agent, Proc. Soc. Exp. Biol. Med. 78:342.
Gross, L., 1959, Effect of thymectomy on development of leukemia in C3H mice inoculated with leukemia “passage” virus, Proc. Soc. Exp. Biol. Med. 100:325.
Gross, L., 1970, Oncogenic Viruses, 2nd ed., Pergamon Press, Elmsford, N.Y.
Gross, L., 1974, The role of viruses in the etiology of cancer and leukemia, J. Am. Med. Assoc. 230:1029.
Hassan, Z. M., and Reese, R. C., 1980, Natural cytotoxicity towards tumor cells: Killing by adherent phagocytic lymph node cells of C57B1 mice, Prepr. Br. Soc. Immunol, Spring, p. 33.
Henney, C. S., 1977, Mechanism of tumor cell destruction, in: Mechanisms of Tumor Immunity (I. Green, S. Cohen, and R. T. McCluskey, eds.), pp. 55–86, Wiley, New York.
Herberman, R. H., and Ortaldo, J. R., 1981, Natural killer cells: Their role in defenses against disease, Science 214:24.
Hethcote, H. W., and Knudson, A. G., Jr., 1978, Model for the incidence of embryonal cancers: Application to retinoblastoma, Proc. Natl. Acad. Sci. USA 75:2453.
Hill, M., and Hillova, J., 1976, Genetic transformation of animal cells with viral DNA of RNA tumor viruses, Adv. Cancer Res. 23:237.
Hopper, D. G., and Pimm, M. V., 1977, Antitumour effects of macrophages in BCG contact therapy of rat tumours, in: The Macrophage and Cancer (K. James, B. McBride, and A. Stuart, eds.), pp. 182–187, Econoprint, Edinburgh.
Huebner, R. J., Gilden, R. V., Toni, R., Hill, R. W., Trimmer, R. W., Fish, D. C., and Sass, B., 1976, Prevention of spontaneous leukemia in AKR mice by type-specific immunosuppression of endogenous ecotropic virogenes, Proc. Natl. Acad. Sci. USA 73:4633.
Hugoson, G., Lageröf, B., and Thorell, B., 1977, The effect of chronic protozoan infection by Babesia rodhaini on leukemogenesis in mice, Int. J. Cancer 20:947.
Humphrey, J. H., and White, R. G., 1970, Immunology for Students of Medicine, 3rd ed., pp. 7–8, Davis, Philadelphia.
Ihle, J. N., Charman, H., and Gilden, R. V., 1980, Comparative biology of mammalian retroviruses, Cancer Biol. Rev. 1:133.
James, K., 1977, The influence of tumour cell products on macrophage function in vitro and in vivo: A review, in: The Macrophage and Cancer (K. James, B. McBride, and A. Stuart, eds.), pp. 225–246, Econoprint, Edinburgh.
Jansson, B., and Révész, L., 1976, A deductive approach to the analysis of the growth of ascites tumor cell populations, in: Methods in Cancer Research, Vol. 13 (H. Busch, ed.), pp. 227–299, Academic Press, New York.
Kaiser, C. W., and Reif, A. E., 1975, Immunological monitoring and adjuvant immunotherapy of selected cancer patients, in: Immunity and Cancer in Man: An Introduction (A. E. Reif, ed.), pp. 19–46, Dekker, New York.
Kaplan, H. S., 1967, On the natural history of the murine leukemias: Presidential address, Cancer Res. 27:1325.
Kaplan, H. S., 1974, Leukemia and lymphoma in experimental and domestic animals, Ser. Haematol. 7:94.
Kaplan, H. S., 1977, Interaction between radiation and viruses in the induction of murine thymic lymphomas and lymphatic leukemias, in: Radiation-Induced Leukemogenesis and Related Viruses (J. F. Duplan, ed.), pp. 1–17, North-Holland, Amsterdam.
Kaplan, H. S., Hirsch, B. B., and Brown, M. R., 1956, Indirect induction of lymphomas in irradiated mice. IV. Genetic evidence of the origin of the tumor cells from thymic grafts, Cancer Res. 16:434.
Kapp, J. A., Pierce, C. W., Theze, J., and Benacerraf, B., 1978, Modulation of immune responses by suppressor T cells, Fed. Proc. 37:2361.
Kassel, R. L., and Old, L. J. 1976, Plasma-mediated leukemia cell destruction. I. Stabilization and concentration of the active fraction, Proc. Am. Assoc. Cancer Res. 17:172.
Kassel, R. L., Old, L. J., Carswell, E. A., Fiore, N. C., and Hardy, W. D., Jr., 1973, Serum mediated leukemia cell destruction in AKR mice, J. Exp. Med. 138:925.
Keller, R., 1979, A consideration of the involvement of mononuclear phagocytes in tumor resistance, in: Current Trends in Tumor Immunology (S. Ferrone, S. Gorini, R. B. Herberman, and R. A. Reisfeld, eds.), pp. 121–138, Garland STPM Press, New York.
Kindred, B., Bösing-Schneider, R., and Corley, R. B., 1979, In vivo activity of a nonspecific T cell-replacing factor, J. Immunol. 122:350.
Klein, G., 1975, Immunological surveillance against neoplasia, in: The Harvey Lectures, Series 69, pp. 71–102, Academic Press, New York.
Klein, G., 1980. Immune and non-immune control of neoplastic development: Contrasting effects of host and tumor evolution, Cancer 45:2486.
Klein, J., 1975, Biology of the Mouse Histocompatibility-2 Complex, Springer-Verlag, Berlin.
Knudson, A. G., Jr., 1977, Genetics and etiology of human cancer, Adv. Hum. Genet. 8:1.
Kobayashi, H., Takeichi, N., and Kuzumaki, N., 1978, Xenogenization of Lymphocytes, Erythroblasts, and Tumor Cells, Hokkaido University Medical Library Series, Vol. 10, Hokkaido University School of Medicine, Hokkaido.
Koeffler, H. P., and Golde, D. W., 1981, Chronic myelogenous leukemia—New concepts, N. Engl. J. Med. 304:1201.
Köhler, G., and Milstein, C., 1975, Continuous cultures of fused cells secreting antibodies of predefined specificity, Nature (London) 256:495.
Kumar, V., Goldschmidt, L., Eastcott, J. W., and Bennett, M., 1978, Mechanisms of genetic resistance to Friend virus leukemia in mice. IV. Identification of a gene (Fv-3) regulating immunosuppression in vitro, and its distinction from Fv-2 and genes regulating marrow allograft reactivity, J. Exp. Med. 147:422.
Kurth, R., Fenyö, E. M., Klein, E., and Essex, M., 1979, Cell-surface antigens induced by RNA tumour viruses, Nature (London) 279:197.
Lala, P. K., 1971, Studies on tumor cell population kinetics, in: Methods in Cancer Research, Vol. 6 (H. Busch, ed.), pp. 3–95, Academic Press, New York.
Leventhal, B. G., Civin, C. I., and Reaman, G., 1980, Markers in human lymphoid tumors, in: Cancer Markers (S. Sell, ed.), pp. 89–113, Humana Press, Clifton, N.J.
Levinthal, J. D., Buffett, R. F., and Furth, J., 1959, Prevention of viral leukemia of mice by thymectomy, Proc. Soc. Exp. Biol. Med. 100:610.
Levy, M. H., and Wheelock, E. F., 1974, The role of macrophages in defense against neoplastic disease, Adv. Cancer Res. 20:131.
Law, L. W., and Miller, J. H., 1950, Observations on the effect of thymectomy on spontaneous leukemias in mice of high leukemia strains RIL and C58, J. Natl. Cancer Inst. 11:253.
Likhite, V. V., 1978, Review of tumor enchancement, in: The Handbook of Cancer Immunology, Vol. 4 (H. Waters, ed.), pp. 235–276, Garland STPM Press, New York.
Lilly, F., and Pincus, T., 1973, Genetic control of murine viral leukemogenesis, Adv. Cancer Res. 17:231.
Lilly, F., Boyse, A. E., and Old, L. J., 1964, Genetic basis of viral leukemogenesis, Lancet 2:1207.
Lilly, F., Duran-Reynals, M. L., and Rowe, W. P., 1975, Correlation of early murine leukemia virus titer and H-2 type of spontaneous leukemia in mice of the BALB x AKR cross: A genetic analysis, J. Exp. Med. 141:882.
Louie, S., Daoust, P. R., and Schwartz, R. S., 1980, Immunodeficiency and the pathogenesis of non-Hodkins lymphoma, Semin. Oncol. 7:267.
Magrath, I. T., 1981, Lymphocyte differentiation: An essential basis for the comprehension of lymphoid neoplasia, J. Natl. Cancer Inst. 67:501.
Marshak-Rothstein, A., Fink, P., Gridley, T., Raulet, D. H., Bevan, M. J., and Gefter, M. L., 1979, Properties and applications of monoclonal antibodies directed against determinants of the Thy-1 locus, J. Immunol. 122:2491.
Mathé, G., Pouillart, P., and Lapeyraque, F., 1969, Active immunotherapy of L1210 leukemia applied after the graft of tumor cells, Brit. J. Cancer 23:814–824.
McBride, W. H., Peters, L. J., Mason, K. A., Barrow, G., and Milas, L., 1977, In vivo anti-tumour activity of C. parvum stimulated peritoneal exudate cells, in: The Macrophage and Cancer (K. James, B. McBride, and A. Stuart, eds.), pp. 173–181, Econoprint, Edinburgh.
Mendelsohn, M. L., 1969, Cell cycle kinetics and mitotically linked chemotherapy, Cancer Res. 29:1390.
Meruelo, D., Nimelstein, S. H., Jones, P. P., Lieberman, M., and McDevitt, H. O., 1978, Increased synthesis and expression of H-2 antigens on thymocytes as a result of radiation leukemia virus infection: A possible mechanism for H-2 linked control of virus-induced neoplasia, J. Exp. Med. 147:470.
Metcalf, D., 1956, The thymic origin of the plasma lymphocytosis stimulating factor, Br. J. Cancer 10:442.
Metcalf, D., 1964, Functional interactions between the thymus and other organs, in: The Thymus (D. Metcalf, V. Defendi, and H. Koprowski, eds.), pp. 53–73, Wistar Institute Press, Philadelphia.
Metcalf, D., 1966, Histologic and transplantation studies on preleukemic thymus of the AKR mouse, J. Natl. Cancer Inst. 37:425.
Mikulski, S. M., and Muggia, F. M., 1978, The suppressor mechanisms and their significance in tumor immunology, Cancer Immunol. Immunother. 4:139.
Milas, L., and Scott, M. T., 1978, Antitumor activity of Corynebacterium parvum, in: Advances in Cancer Research, Vol. 26 (G. Klein and S. Weinhouse, eds.), pp. 257–306, Academic Press, New York.
Miller, J. F. A. P., 1959, Fate of subcutaneous thymus grafts in thymectomized mice inoculated with leukemic filtrate, Nature (London) 184: 1809.
Mogensen, S. C., 1979, Role of macrophages in natural resistance to virus infections, Microbiol. Rev. 43:1.
Murphy, E. D., 1966, Characteristic tumors, in: Biology of the Laboratory Mouse (E. L. Green, ed.), pp. 521–562, McGraw-Hill, New York.
Nadler, L. M., Ritz, J., Reinherz, E. L., and Schlossman, S. F., 1981, Cellular origins of human leukemias and lymphomas, in: Leukemia Markers (W. Knapp, ed.), pp. 3–17, Academic Press, New York.
Nelson, D. S., 1976, Macrophages: Perspectives and prospects, in: Immunology of the Macrophage (D. S. Nelson, ed.), pp. 617–621, Academic Press, New York.
Normann, S. J., Schardt, M., and Sorkin, E., 1977, Do tumors escape surveillance by depression of macrophage inflammation?, in: The Macrophage and Cancer (K. James, B. McBride, and A. Stuart, eds.), pp. 247–257, Econoprint, Edinburgh.
Nossal, G. J. V., and Gorrie, J., 1964, Studies on the emigration of thymic cells in young guinea pigs, in: The Thymus in Immunobiology (R. A. Good and A. E. Gabrielsen, eds.), pp. 288–290, Harper & Row, New York.
Old, L. J., 1981, Cancer immunology: The search for specificity—G. H. A. Clewes memorial lecture, Cancer Res. 41:361.
Old, L. J., and Boyse, E. A., 1964, Immunology of experimental tumors, Annu. Rev. Med. 15:167.
Old, L. J., and Stockert, E., 1977, Immunogenetics of cell surface antigens of mouse leukemia, Annu. Rev. Genet. 11:127.
Old, L. J., Benacerraf, B., Clarke, D. A., Carswell, E., and Stockert, E., 1961, The role of the endothelial system in the host reaction to neoplasia, Cancer Res. 21:1281.
Old, L. J., Boyse, E. A., Clarke, D. A., and Carswell, E. A., 1962, Antigenic properties of chemically induced tumors, Ann. N.Y. Acad. Sci. 101:80.
Parkinson, D. R., Schwartz, R. S., and Sutherland, D. C., 1981, Viruses, genes and lymphoma, Contemp. Hematol. Oncol. 2:467.
Penn, I., and Starzl, T. E., 1973, The effect of immunosuppression on cancer, in: Seventh National Cancer Conference Proceedings, pp. 425–436, Lippincott, Philadelphia.
Perkins, E. H., and Cacheiro, L. H., 1980, Immunodepression, a noncontributor to radiation-induced leukemogenesis of the RFM mouse, Cancer Res. 40:357.
Perry, L. L., Benacerraf, B., and Greene, M. I., 1978, Regulation of the immune response to tumor antigen. IV. Tumor antigen-specific suppressor factor(s) bear I-J determinants and induce suppressor T cells in vivo, J. Immunol. 121:2144.
Persson, U., Hammarström, L., Möller, E., Möller, G., and Smith, C. T. E., 1978, The role of adherent cells in B and T lymphocyte activation, Immunol. Rev. 40:78.
Pierce, G. B., and Johnson, L. D., 1971, Differentiation and cancer, In Vitro 7:140.
Pitot, H. C., 1978, Fundamentals of Oncology, Dekker, New York.
Prager, M. D., and Baechtel, F. S., 1973, Methods for modification of cancer cells to enhance their antigenicity, in: Methods in Cancer Research (H. Busch, ed.), pp. 339–400, Academic Press, New York.
Prehn, R. T., 1976, Tumor progression and homeostasis, Adv. Cancer Res. 23:203.
Raabe, O. G., Book, S. A., and Parks, N. J., 1980, Bone cancer from radium: Canine dose response explains data for mice and humans, Science 208:61.
Rappaport, H., and Baroni, C., 1962, A study of the pathogenesis of malignant lymphoma induced in the Swiss mouse by 7,12-dimethylbenz(a)anthracene injected at birth, Cancer Res. 22: 1067.
Reif, A. E., 1961, Radiation carcinogenesis at high dose-response levels: A hypothesis, Nature (London) 190:415.
Reif, A. E., 1975, Immune defenses against initiation of tumors, in: Immunity and Cancer in Man: An Introduction (A. E. Reif, ed.), pp. 1–18, Dekker, New York.
Reif, A. E., 1978, Evidence for organ specificity of defenses against tumors, in: The Handbook of Cancer Immunology, Vol. 1 (H. Waters, ed.), pp. 173–249, Garland STPM Press, New York.
Reif, A. E., 1981a, Effect of cigarette smoking on susceptibility to lung cancer, Oncology 38:76.
Reif, A. E., 1981b, The causes of cancer, Am. Sci. 69:437.
Reif, A. E., and Allen, J. M. V., 1964, The AKR thymic antigen and its distribution in leukemias and nervous tissues, J. Exp. Med. 120:413.
Reif, A. E., and Allen, J. M., 1966, The antigenic stability of 3 AKR leukemias on isotransplantation and the serologic detection of thymus-derived leukemia cells, Cancer Res. 26:123.
Reif, A. E., and Kim, C.-A. H., 1971a, Leukemia L1210 trials with antileukemia serum and Bacillus Calmette-Guérin, Cancer Res. 31:1606.
Reif, A. E., and Kim, C.-A. H., 1971b, Specificity of rabbit antisera against mouse leukaemia cells in vitro, Immunology 20:1087.
Robinson, M. K., Manly, K. F., and Evans, M. J., 1980, Immunosuppression by 334C murine leukemia virus: Viral specificity and the activation of immunosuppressive effects during cloned viral leukemogenesis, J. Immunol. 124:1022.
Roder, J. C., and Kiessling, R., 1979, Natural killer cells: Genetic control, specificity, and the mechanism of target cell recognition, in: Current Trends in Tumor Immunology (S. Ferrone, S. Gorini, R. B. Herberman, and R. A. Reisfeld, eds.), pp. 31–47, Garland STPM Press, New York.
Rotter, V., and Trainin, N., 1979, Role thymic hormone (THF) and of a thymic plasma recirculating factor (TPRF) in the modulation of human lymphocyte response to PHA and Con A, J. Immunol. 122:414.
Rowe, W. P., Hartley, J. W., and Kozak, C. A., 1981, in: The Jackson Laboratory Fiftieth Anniversary Symposium (E. S. Russell, ed.), pp. 291–295, Liss, New York.
Sainte-Marie, G., 1973, Cell migration and the thymus, in: Contemporary Topics in Immunobiology, Vol. 2 (A. J. S. Davies and R. L. Carter, eds.), pp. 111–117, Plenum Press, New York.
Saxon, A., Stevens R. H., and Golde, D. W., 1979, Helper and suppressor T-lymphocyte leukemia in ataxia telangiectasia, N. Engl. J. Med. 300:700.
Schäfer, W., Schwarz, H., Thiel, H.-J., Fischinger, P. J., and Bolognesi, D. P., 1977, Properties of mouse leukemia viruses. XIV. Prevention of spontaneous AKR leukemia by treatment with group-specific antibody against the major virus gp71 glycoprotein, Virology 83:207.
Schocket, A. L., Malesky, E. V., and Köhler, P. F., 1981, Lymphocytotoxic antibodies in cancer, Cancer Immunol. Immunother. 12:43.
Schwartz, R. S., 1975, Another look at immunological surveillance, N. Engl. J. Med. 293:181.
Shaw, J., Monticone, V., and Paetkau, V., 1978, Partial purification and molecular characterization of a lymphokine (costimulator) required for the mitogenic response of mouse thymocytes in vitro, J. Immunol. 120:1967.
Siegel, B. V., 1978, Tumor immunity: An overview, Am. J. Pathol. 93:515.
Siegler, R., and Rich, M. A., 1963, Unilateral histogenesis of AKR thymic lymphoma, Cancer Res. 23:1669.
Siegler, R. S., Geldner, J., and Rich, M. A., 1964, Histogenesis of thymic lymphoma induced by a murine leukemia virus (Rich), Cancer Res. 24:444.
Skipper, H. E., 1968, Cellular kinetics associated with “curability” of experimental leukemias, in: Perspective in Leukemia (W. Dameshek and R. M. Dutcher, eds.), pp. 187–216, Grune & Stratton, New York.
Skipper, H. E., 1971, Cancer chemotherapy is many things—Clowes memorial lecture, Cancer Res. 31:1173.
Smith, C., 1964, The microscopic anatomy of the thymus, in: The Thymus in Immunobiology (R. A. Good and A. E. Gabrielsen, eds.), pp. 71–84, Harper & Row, New York.
Snell, G. D., 1978, T cells, T cell recognition structures, and the major histocompatibility complex, Immunol. Rev. 38:3.
Snell, G. D., Dausset, J., and Nathenson, S., 1976, Histocompatibility, Academic Press, New York.
Stück, B., Old, L. J., and Boyse, E. A., 1964, Antigenic conversion of established leukemias by an unrelated leukaemogenic virus, Nature (London) 202:1016.
Stutman, O., 1975, Immunodepression and malignancy, Adv. Cancer Res. 22:261.
Tai, A., Burton, R. C., and Warner, N. L., 1980, Differential natural killer cell reactivity against T cell lymphomas by cells from normal or stimulated mice, J. Immunol. 124:1705.
Talmadge, J. E., Mayers, K. M., Prieur, D. J., and Starkey, J. R. 1980, Role of NK cells in tumour growth and metastasis in beige mice, Nature (London) 284:622.
Tevethia, S. S., Zarling, J. M., and Flax, M. H., 1976, Macrophages and the destruction of syngeneic virus-induced tumors, in: Immunology of the Macrophage (D. S. Nelson, ed.), pp. 509–533, Academic Press, New York.
Till, J. E., 1981, Cellular diversity in the blood-forming system, Am. Sci. 69:522–527.
Tooze, J., 1973, The Molecular Biology of Tumor Viruses, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
Treves, A. J., 1978, In vitro induction of cell-mediated immunity against tumor cells by antigen-fed macrophages, Immunol. Rev. 40:205.
Tung, J.-S., and Fleissner, E., 1980, Amplified env and gag products on AKR cells: Origin from different leukemia virus genomes, J. Exp. Med. 151:975.
van Ewijk, W., Soest, P. L. v., and Engh, G. J. van der, 1981, Fluorescence analysis and anatomic distribution of mouse T lymphocyte subsets defined by monoclonal antibodies to the antigens Thy-1, Lyt-1, Lyt-2, and T-200, J. Immunol. 127:2594.
van Fournier, D., Weber, E., Hoeffken, W., Bauer, M., Kubli, F., and Barth, V., 1980, Growth rate of 147 mammary carcinomas, Cancer 45:2198.
Williams, A. H., Taylor, C. R., Higgins, G. R., Quinn, J. J., Schneider, B. K., Swanson, V., Parker, J. W., Pattengale, P. K., Chandor, S. B., Powars, D., Lincoln, T. L., Tindle, B. H., and Lukes, R. J., 1978, Childhood lymphoma-leukemia, Cancer 42:171.
Wright, P. W., and Loop, S. M., 1979, Amplification of the proliferative response to alloantigen by a factor present in an extract of syngeneic thymic lymphoid cells: Demonstration of optimal conditions and target cell for factor activity, J. Immunol. 122:2435.
Yarkoni, E., and Rapp, H. J., 1980, Influence of surfactant concentration on the antitumor activity of emulsified components of mycobacteria, Cancer Res. 40:975.
Zaleski, M., and Klein, J., 1978, Genetic control of the immune response to Thy-1 antigens, Immunol. Rev. 38:120.
Zbar, B., Canti, G., Rapp, H. J., Ashley, M. P., Sukumar, S., and Bast, R. C., Jr., 1980, Immu-noprophylaxis of syngeneic methylcholanthrene-induced murine sarcomas with Bacillus Calmette-Guérin and tumor cells, Cancer Res. 40:1036.
Zöller, M., and Matzku, S., 1980, Characterization of natural cytotoxicity in vitro in a spontaneous rat tumor model, J. Immunol. 124:1683.
Zubrod, C. G., 1978, Selective toxicity of anticancer drugs—Presidential address, Cancer Res. 38:4377.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1983 Plenum Press, New York
About this chapter
Cite this chapter
Reif, A.E. (1983). Immunopathology of Malignant Disease in Mice Leukemias and Lymphomas, Stalking-Horses for Human Counterparts. In: Rose, N.R., Siegel, B.V. (eds) Immunopathology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9275-4_9
Download citation
DOI: https://doi.org/10.1007/978-1-4615-9275-4_9
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4615-9277-8
Online ISBN: 978-1-4615-9275-4
eBook Packages: Springer Book Archive