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Immunopathology of Delayed Hypersensitivity

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Book cover Immunopathology

Abstract

The term “delayed hypersensitivity” may be defined as an immunologically specific inflammatory reaction slowly evolving at the site of injection of antigen. The reaction usually becomes apparent grossly only after several hours. The gross appearance with erythema and induration reaches a maximum at 24 to 48 hr. Histologically, the reaction is characteristic, being composed predominantly of lymphocytes and macrophages. Because of a difficulty in distinguishing between certain lymphocytes and macrophages in routine histolotical sections, they are often collectively referred to as mononuclear cells.

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Authors and Affiliations

  1. Department of Pathology, University of Connecticut Health Center, Farmington, Connecticut, 06032, USA

    Takeshi Yoshida & Matsunobu Suko

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  1. Takeshi Yoshida
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  2. Matsunobu Suko
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Editors and Affiliations

  1. The Johns Hopkins University, Baltimore, Maryland, USA

    Noel R. Rose

  2. Oregon Health Sciences University, Portland, Oregon, USA

    Benjamin V. Siegel

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© 1983 Plenum Press, New York

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Yoshida, T., Suko, M. (1983). Immunopathology of Delayed Hypersensitivity. In: Rose, N.R., Siegel, B.V. (eds) Immunopathology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9275-4_14

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  • DOI: https://doi.org/10.1007/978-1-4615-9275-4_14

  • Publisher Name: Springer, Boston, MA

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