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Neurobiology of Cerebrospinal Fluid 2 pp 497–516Cite as

Perinatal Intraventricular Hemorrhage

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Abstract

Intraventricular hemorrhage (IVH) is at present one of the most commonly encountered acute perinatal insults to brain and is a major cause of death in low-birth-weight infants.12,30,67,89,90 IVH is associated clinically with respiratory distress in from 50 to 95% of cases and is the most common neuropathological finding in infants dying with this disorder.44 Improvement in the management of the complex of problems faced by the premature neonate has led to the survival of many infants who have sustained IVH. Recent statistics of longterm morbidity indicate an ultimately poor outcome with a high incidence of developmental retardation, hydrocephalus, cerebral palsy, and learning disability.16,35–38 If severe IVH is associated with intraparenchymal hemorrhage, then the mortality is 88% in preterm newborns less than 1000 g and is 36% in preterm neonates greater than 1000 g with most survivors severely afflicted.48a Therefore, accurate diagnosis of IVH, identification of prognostic factors, and management of posthemorrhagic complications have become of increasing importance in the neonatal intensive care unit population.

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Authors and Affiliations

  1. Division of Neonatology, Department of Pediatrics, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, Pennsylvania, 17033, USA

    Jonathan Hellmann M.B., B.Ch., F.C.P. (S.A.)

  2. Division of Pediatric Neurology, Department of Pediatrics, New York Hospital, Cornell Medical Center, New York, New York, 10021, USA

    Robert C. Vannucci M.D.

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  1. Jonathan Hellmann M.B., B.Ch., F.C.P. (S.A.)
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  2. Robert C. Vannucci M.D.
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Editors and Affiliations

  1. Division of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia, USA

    James H. Wood M D

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Hellmann, J., Vannucci, R.C. (1983). Perinatal Intraventricular Hemorrhage. In: Wood, J.H. (eds) Neurobiology of Cerebrospinal Fluid 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9269-3_29

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