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The Uricosuric Action of Protein in Man

Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 122A)

Abstract

The influence of dietetic measures on uric acid metabolism was repeatedly investigated (1,2,3,6). In our studies we were able to show that intravenously administered amino acids display a definite uricosuric effect (5). Our aim was then to investigate whether the uric acid metabolism can also be affected under oral application of purine free protein by modifying the dietary protein portion.

Keywords

Uric Acid Serum Uric Acid Level Uric Acid Concentration Uric Acid Excretion Formula Diet 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Bien, E.J., T.F. Yü, J.D. Benedict, A.B. Gutman, D.J. Stetten: The relation of dietary nitrogen consumption to the rate of uric acid synthesis in normal and gouty man. J. clin. invest 32(1953), 778PubMedCrossRefGoogle Scholar
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    Bowering, J., D.H. Calloway, S. Margen, W.A. Kaufmann: Dietary protein level and uric acid metabolism in normal man. J. nutr. 100 (1969), 249Google Scholar
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    Harding,V.J., K.D. Allin, B.A. Eagles: Influence of fat and carbohydrate diets upon the level of blood uric acid. J.Biol.Chem. 74(1927), 631Google Scholar
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    Löffler et al: Ernährung des Gichtkranken Klinikarzt 6 (1977), 865Google Scholar
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    Matzkies, F., G. Berg: The uricosuric action of amino acids J.Clin.Chem.Clin.Biochem. 14(1976), 308Google Scholar
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    Waslien, C.I., D.H. Calloway, S. Margen: Uric acid production of men fed graded amounts of egg protein and yeast nucleic acid. Am.J.Clin.Nutr. 21 (1968), 892PubMedGoogle Scholar
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    Wilson, D., Ch. Bishop, J.H. Talbott: A factorial experiment to test the effect of various types of diets on uric acid excretion of normal human subjects. J. appl. Physiol. 4(1952), 560PubMedGoogle Scholar
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    Zöllner, N.: Die Manifestation der Gicht Beobachtungen über das Zusammenwirken von Ernährung und biochemischer Individualität Internist 18 (1977), 474PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  1. 1.Abteilung für Stoffwechsel und Ernährung in der Medizinischen Klinik mit PoliklinikUniversität Erlangen-NürnbergErlangenGermany

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