Abstract
The ability to discriminate self from non-self is perhaps one of the most important biological mechanisms in the life cycle of the vertebrates since the absence of such a mechanism would ultimately lead to an autoimmune reaction and the subsequent death of the organism during early stages of development. It is hoped that investigations into the abnormal breakdown of this discrimination during autoimmunity will lead to a clearer understanding of the mechanisms controlling self-tolerance in normal animals and man.
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© 1979 Plenum Press, New York
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Roder, J.C., Bell, D.A., Singhal, S.K. (1979). The Control of Autoreactive Lymphocytes by a Receptor Blockade Mechanism. In: Müller-Ruchholtz, W., Müller-Hermelink, H.K. (eds) Function and Structure of the Immune System. Advances in Experimental Medicine and Biology, vol 114. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9101-6_44
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DOI: https://doi.org/10.1007/978-1-4615-9101-6_44
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