Ontogenetic Differentiation of Epithelial and Non-Epithelial Cells in the Human Thymus

  • B. von Gaudecker
  • H. K. Müller-Hermelink
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 114)


Most electron microscopical and functional reports dealing with the ontogenesis of the thymus in laboratory animals and man (1,2) consider almost only the differentiation of its typical “lymphoid” organization. The aim of the present study was to determine whether the main epithelial and mesenchymal structures develop before, or at the same time as the first lymphoid cells are seen in the thymus, i.e. whether the differentiation of a characteristic microecology may be regarded as a necessary prerequisite for lymphoid colonization.


Semi Thin Section Myoid Cell Peripheral Lymphatic Tissue Thymic Medulla Interdigitating Reticulum Cell 
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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • B. von Gaudecker
    • 1
  • H. K. Müller-Hermelink
    • 2
  1. 1.Institute of AnatomyUniversity of KielKielW. Germany
  2. 2.Institute of PathologyUniversity of KielKielW. Germany

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