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Human Interferon: Large Scale Production in Embryo Fibroblast Cultures

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Human Interferon

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 110))

Abstract

Initial exploratory tests, and trials of the use of exogenous interferon in man have had fairly promising results (1–7); however, further more extensive trials will probably be restricted by limitations in the supply of interferon. Almost all trials of interferon in man have, up to now, been performed using leukocyte-derived interferon produced by induction with Sendai virus (8). This system of production is dependent on the supply of human blood buffy coats, and this factor alone restricts expansion of production from present levels.

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Author information

Authors and Affiliations

  1. Department of Human Biology, Division of Microbiology, Rega Institute, University of Leuven, B-3000, Leuven, Belgium

    V. G. Edy, J. VanDamme, A. Billiau & P. DeSomer

Authors
  1. V. G. Edy
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  2. J. VanDamme
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  3. A. Billiau
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  4. P. DeSomer
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Editor information

Editors and Affiliations

  1. The University of Vermont, Burlington, Vermont, USA

    Warren R. Stinebring

  2. W. Alton Jones Cell Science Center, Lake Placid, New York, USA

    Paul J. Chapple

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© 1978 Plenum Press, New York

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Edy, V.G., VanDamme, J., Billiau, A., DeSomer, P. (1978). Human Interferon: Large Scale Production in Embryo Fibroblast Cultures. In: Stinebring, W.R., Chapple, P.J. (eds) Human Interferon. Advances in Experimental Medicine and Biology, vol 110. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-9080-4_5

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  • DOI: https://doi.org/10.1007/978-1-4615-9080-4_5

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4615-9082-8

  • Online ISBN: 978-1-4615-9080-4

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