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Results of a Five-Year Study of the Curative Effect of Double Stranded Ribonucleic Acid in Viral Dermatoses and Eye Diseases

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Human Interferon

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 110))

Abstract

Double stranded RNA obtained from non-permissive E. coli cells infected with f2-phage was tested in 5 hospitals in viral dermatoses such as herpes simplex recidivans, herpes zoster, male genikeratonconjunctivitis herpetica and conjunctivitis lignosa. The results of clinical tests indicate that the preparation of phage double stranded RNA applied topically is harmless for man and has, in the majority of cases, a beneficial effect in the disease. This conclusion was based on the judgment of physicians, opinion of patients expressed in a questionnaire, and, results of a double-blind experiment.

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Author information

Authors and Affiliations

  1. Institute of Virology, Slovak Academy of Sciences, Bratislava, Slovakia

    L. Borecky & V. Lackovic

  2. Dermatological Clinic, University Hospital, Bratislava, Slovakia

    J. Buchvald

  3. Children’s Clinic, Postgraduate School of Medicine, Bratislava, Slovakia

    E. Adlerova

  4. County Hospital, Banska Bystrica, Slovakia

    I. Stodola

  5. Eye Clinic, University Hospital, Olomouc, Czech Republic

    E. Obrucnikova

  6. School of Pharmacy, Comenius University, Bratislava, Slovakia

    Z. Gruntova

  7. Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, Prague, Czech Republic

    J. Doskocil

Authors
  1. L. Borecky
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  2. J. Buchvald
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  3. E. Adlerova
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  4. I. Stodola
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  5. E. Obrucnikova
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  6. Z. Gruntova
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  7. V. Lackovic
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  8. J. Doskocil
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Editor information

Editors and Affiliations

  1. The University of Vermont, Burlington, Vermont, USA

    Warren R. Stinebring

  2. W. Alton Jones Cell Science Center, Lake Placid, New York, USA

    Paul J. Chapple

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© 1978 Plenum Press, New York

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Borecky, L. et al. (1978). Results of a Five-Year Study of the Curative Effect of Double Stranded Ribonucleic Acid in Viral Dermatoses and Eye Diseases. In: Stinebring, W.R., Chapple, P.J. (eds) Human Interferon. Advances in Experimental Medicine and Biology, vol 110. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-9080-4_14

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  • DOI: https://doi.org/10.1007/978-1-4615-9080-4_14

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  • Print ISBN: 978-1-4615-9082-8

  • Online ISBN: 978-1-4615-9080-4

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