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Interferon Assay Anomaly Variation of Interferon Response with Cell Type and Sialic Acid Content

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Human Interferon

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 110))

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Abstract

Human interferon derived from leukocytes and cultured fibroblast sources has been compared by assay in two human cell systems. The ratio of the activities of the two interferon preparations differed markedly in two assay systems. Neuraminidase treatment had no effect on the activity of either interferon in the more sensitive system but reduced the activity of the fibroblast material in the second system so that the resulting ratio of activities approximated that seen in the first assay system.

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References

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Author information

Authors and Affiliations

  1. Searle Laboratories, Skokie, Illinois, USA

    A. A. Schwartz Ph.D. & D. Villani-Price

Authors
  1. A. A. Schwartz Ph.D.
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  2. D. Villani-Price
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Editor information

Editors and Affiliations

  1. The University of Vermont, Burlington, Vermont, USA

    Warren R. Stinebring

  2. W. Alton Jones Cell Science Center, Lake Placid, New York, USA

    Paul J. Chapple

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© 1978 Plenum Press, New York

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Schwartz, A.A., Villani-Price, D. (1978). Interferon Assay Anomaly Variation of Interferon Response with Cell Type and Sialic Acid Content. In: Stinebring, W.R., Chapple, P.J. (eds) Human Interferon. Advances in Experimental Medicine and Biology, vol 110. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-9080-4_12

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  • DOI: https://doi.org/10.1007/978-1-4615-9080-4_12

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4615-9082-8

  • Online ISBN: 978-1-4615-9080-4

  • eBook Packages: Springer Book Archive

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