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Self-Administration of Sedatives by Humans

  • Roy Pickens
  • Marilyn R. Cunningham
  • Leonard L. Heston
  • Elke Eckert
  • Linda K. Gustafson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 85B)

Abstract

Sedative drugs have many of the same effects as alcohol. Taken in high doses, both produce confusion, difficulty in thinking, emotional lability, and motor incoordination (Isbell et al., 1950). Both also have a high potential for abuse, with tolerance and physiological dependence resulting from chronic, high-dose use (Wikler, 1968). In experimental studies of human alcohol and sedative intoxication, clinical symptoms of intoxication and withdrawal were similar for both compounds, with alcohol substituting for and maintaining physiological dependence previously established to sedative compounds (Fraser et al., 1957).

Keywords

Sedative Drug Slur Speech Preference Ratio Drug Serum Level Motor Incoordination 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Roy Pickens
    • 1
  • Marilyn R. Cunningham
    • 1
  • Leonard L. Heston
    • 1
  • Elke Eckert
    • 1
  • Linda K. Gustafson
    • 2
  1. 1.Psychiatry ResearchUnit University of MinnesotaMinneapolisUSA
  2. 2.Elizabeth Ludeman Development CenterPark ForestUSA

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