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Regulation of Cell Division in Aging Mouse Mammary Epithelium

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Explorations in Aging

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 61))

Abstract

The subject of cellular aging is a matter of considerable importance in comtemporary biology. The characteristics and parameters of these aging processes, as well as the mechanisms which underlie them, are currently investigated by a variety of techniques. At present the most widely used methodology is that of continuous cell culture, in which normal diploid tissue cells, even though provided with every known requirement and stimulus, for growth, nevertheless display an inevitable decline in proliferative capacity, followed by senescent changes and eventual loss of the culture.

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Author information

Authors and Affiliations

  1. University of California, Santz Cruz, CA, 95064, USA

    Charles W. Daniel

Authors
  1. Charles W. Daniel
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Editor information

Editors and Affiliations

  1. Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, USA

    Vincent J. Cristofalo

  2. Medical College of Pennsylvania, Philadelphia, Pennsylvania, USA

    Jay Roberts

  3. Fels Research Institute, Temple University School of Medicine, Philadelphia, Pennsylvania, USA

    Richard C. Adelman

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© 1975 Plenum Press, New York

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Daniel, C.W. (1975). Regulation of Cell Division in Aging Mouse Mammary Epithelium. In: Cristofalo, V.J., Roberts, J., Adelman, R.C. (eds) Explorations in Aging. Advances in Experimental Medicine and Biology, vol 61. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-9032-3_1

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  • DOI: https://doi.org/10.1007/978-1-4615-9032-3_1

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4615-9034-7

  • Online ISBN: 978-1-4615-9032-3

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