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Subcellular Structure and Synthesis of Steroids in the Testis

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The Human Testis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 10))

Abstract

It is becoming increasingly evident that subcellular localization of enzymes, substrates, cofactor systems, transport systems for oxygen, electrons, etc. are factors to be considered in the process of elaboration of steroid hormones. The production of the characteristic array of steroids by specific endocrine tissues, and more important, its control by gonadotropin, cannot at the present time be explained exclusively in terms of enzymes alone. Studies of various gonadal tissues in recent years reveal that the same enzymes or families of enzymes (3ß-hydroxysteroid dehydrogenase-isomerase, 17-hydroxylase, C17,20-lyase, the 19-hydroxylase-aromatase system, 17ß-hydroxysteroid dehydrogenase) are present in testicular tissues, in follicular tissue, in the human corpus luteum and in ovarian interstitial tissue. Yet each of these gonadal elements elaborates its own unique steroidal product.

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Author information

Authors and Affiliations

  1. Endocrine Laboratory, Department of Biochemistry and Medicine, University of Miami School of Medicine, Miami, Florids, USA

    Kenneth Savard

Authors
  1. Kenneth Savard
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Editor information

Editors and Affiliations

  1. Medical Research Institute of Worcester, Inc., Worcester City Hospital, Worcester, Massachusetts, USA

    Eugenia Rosemberg M. D. (Research Director) (Research Director)

  2. University of Washington School of Medicine, Seattle, Washington, USA

    C. Alvin Paulsen M. D. (Professor of Medicine) (Professor of Medicine)

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© 1970 Plenum Press, New York

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Savard, K. (1970). Subcellular Structure and Synthesis of Steroids in the Testis. In: Rosemberg, E., Paulsen, C.A. (eds) The Human Testis. Advances in Experimental Medicine and Biology, vol 10. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9008-8_33

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  • DOI: https://doi.org/10.1007/978-1-4615-9008-8_33

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9010-1

  • Online ISBN: 978-1-4615-9008-8

  • eBook Packages: Springer Book Archive

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