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Protein Purification by Immunoadsorption

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Enzyme Engineering Volume 2

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Abstract

One of the aims of the Molecular Anatomy Program at Oak Ridge is the isolation in quantity of cancer associated antigens and antibodies. Proteins produced in cancer may be new to the host and thus be antigenic; or they may be antigenic because the immunological response apparatus of the host normally does not see them; or finally, if the proteins were produced before and reappeared, the immunological apparatus of the host may have been functioning poorly at the time or may have forgotten that it once saw them. In any case the proteins are antigenic to a proper challenge in an experimental animal.

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References

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Author information

Authors and Affiliations

  1. Molecular Anatomy Program and Chemical Technology and Analytical Chemistry Divisions, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA

    N. G. Anderson, D. W. Holladay, J. E. Caton & J. W. Holleman

Authors
  1. N. G. Anderson
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  2. D. W. Holladay
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  3. J. E. Caton
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  4. J. W. Holleman
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Editor information

Editors and Affiliations

  1. Department of Biochemistry, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19174, USA

    E. Kendall Pye

  2. Department of Pharmacology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, 15261, USA

    Lemuel B. Wingard Jr.

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© 1974 Plenum Press, New York

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Anderson, N.G., Holladay, D.W., Caton, J.E., Holleman, J.W. (1974). Protein Purification by Immunoadsorption. In: Pye, E.K., Wingard, L.B. (eds) Enzyme Engineering Volume 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8897-9_7

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  • DOI: https://doi.org/10.1007/978-1-4615-8897-9_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-8899-3

  • Online ISBN: 978-1-4615-8897-9

  • eBook Packages: Springer Book Archive

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