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Studies of the Distribution of Biologically Active Peptides in the Brain

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Hypothalamic Peptide Hormones and Pituitary Regulation

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 87))

Abstract

A number of biologically active peptides have been isolated in recent years. Among these, the “hypothalamic hormones”-luteinizing hormone releasing hormone (LHRH) (1,2), thyrotropin releasing hormone (TRH) (3,4), and growth hormone release inhibiting hormone (somatostatin) (5,6,7)-play very specific roles in regulating the anterior pituitary. In addition, these hormones may act as neurotransmitters or neuromodulators at sites distant from the median eminence. The functions of other peptides, such as substance P (8) and neurotensin (9), remain to be determined.

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Author information

Authors and Affiliations

  1. Section on Pharmacology, Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, Maryland, 20014, USA

    Michael J. Brownstein

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  1. Michael J. Brownstein
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Editors and Affiliations

  1. University of Texas Health Science Center at Dallas, USA

    John C. Porter

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© 1977 Plenum Press, New York

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Brownstein, M.J. (1977). Studies of the Distribution of Biologically Active Peptides in the Brain. In: Porter, J.C. (eds) Hypothalamic Peptide Hormones and Pituitary Regulation. Advances in Experimental Medicine and Biology, vol 87. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8849-8_3

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  • DOI: https://doi.org/10.1007/978-1-4615-8849-8_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-8851-1

  • Online ISBN: 978-1-4615-8849-8

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