Skip to main content

Ant Venoms: A Study of Venom Diversity

  • Chapter
Pesticide and Venom Neurotoxicity

Abstract

Ant venoms appear to represent an almost untapped reservoir of information capable of adding several exciting chapters to the story of toxinology. Ants share with some bees and wasps the distinction of being the only truly social group of venomous animals. This fact implies that most of the venomous individuals belong to an essentially sterile class of worker individuals, and that survival of the species depends on colony rather than individual survival. Unlike social bees and wasps, which use their stings solely for defense, ant stings are utilized for a variety of additional functions, including prey capture and the elaboration of trail, sex, aggregation, and alarm pheromones. In parallel with the evolutionary development of varied stinging behaviors were major changes in the venom composition and the sting apparatus itself. This plasticity in form, function, and composition associated with the sting apparatus may be correlated with the success of ants in dominating most of the terrestrial environments.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Androuny, G. A., Derbes, V. J., and Jung, R. C., 1959, Isolation of a hemolytic component of fire ant venom, Science 130: 449.

    Article  Google Scholar 

  • Baer, H., Liu, D. T., Hooton, M., Blum, M., James, F., Schmid, W. H., 1977, Fire ant allergy: isolation of three allergenic proteins from whole venom, J. Allergy clin. Immunol. (in press).

    Google Scholar 

  • Bernard, F., 1968, Les fourmis(Hymenoptera Formicidae) dEurope occidentale et septentrionale. Faune de lEurope et du Bassin Mediterreen, no. 3, Masson et Cie, Paris.

    Google Scholar 

  • Blum, M., 1966, The source and specificity of trail pheromones in Termitopone, Monomorium and Huberia, and their relation to those of some other ants, Proc. R. Ent. Soc. Lond. (A), 41: 155.

    Google Scholar 

  • Blum, M. S., 1974, Myrmicine trail pheromones: specificity, source, and significance, J. N. Y. Ent. Soc. 82: 141.

    Google Scholar 

  • Blum, M., and Callahan, P. S., 1963, The venom qlands of Pseudomyrmex pallidus (F. Smith), Psyche 70: 69.

    Article  CAS  Google Scholar 

  • Blum, M., and Ross, G. N., 1965, Chemical releasers of social behaviour V. Source, specificity, and properties of the odour trail pheromone of Tetramorium guineense (F.) (Formicidae: Myrmicinae), J. Insect Physiol. 11: 857.

    Article  CAS  Google Scholar 

  • Blum, M., Walker, J. R., Callahan, P. S., and Novak, A. F., 1958, Chemical, insecticidal, and antibiotic properties of fire ant venom, Science 128: 306.

    Article  PubMed  CAS  Google Scholar 

  • Blum, M., Moser, J. X., and Cordero, A. O., 1964, Chemical releasers of social behavior. II. Source and specificity of the odor trail substances in four attine genera. (Hymenoptera: Formi cidae ), Psyche 71: 1.

    Google Scholar 

  • Brand, J. M., Blum, M. S., Fales, H. M., and MacConnell, J. G., 1972, Fire ant venoms: comparative analyses of alkaloidal components, Toxicon 10: 259.

    Article  PubMed  CAS  Google Scholar 

  • Brand, J. M., Blum, M. S., Ross, H. H., 1973, Biochemical evolution in fire ant venoms, Insect Biochem. 3: 45.

    Article  CAS  Google Scholar 

  • Brand, J. M., Blum, M. S., Lloyd, H. A., and Fletcher, D. J. C., 1974, Monoterpene hydrocarbons in the poison gland secretion of the ant Myrmicaria natalensis (Hymenoptera: Formicidae), Ann, ent. Soc. Am. 67: 525.

    CAS  Google Scholar 

  • Brothers, D. J., 1975, Phylogeny and classification of the aculeate Hymenoptera, with special reference to Mutillidae, Univ Kansas Sci. Bull. 50: 483.

    Google Scholar 

  • Brown, W. L., Jr., 1954, Remarks on the internal phylogeny and subfamily classification of the family Formicidae, Insectes Sociaux 1: 21.

    Article  Google Scholar 

  • Buffkin, D. C., and Russell, F. E., 1972, Some chemical and pharmaco-logical properties of the venom of the imported red fire ant, Solenopsis saevissima richteri, Toxicon 10: 526.

    Google Scholar 

  • Bucherl, W., 1971a, Classification, biology and venom extraction of scorpions, in: Venomous Animals and their Venoms, Vol. 3, ( W. Bucherl and E. E. Buckley, eds) pp. 317–349, Academic Press, New York.

    Google Scholar 

  • Bucherl, W., 1971b, Soiders, in: Venomous Animals and their Venoms, Vol. 3, ( W. Bucherl and E. E. Buckley, eds) pp. 197–277, Academic Press, New York.

    Google Scholar 

  • Buren, W. F., 1958, A review of the species of Crematogaster, Sensu Stricto, in North America (Hymenoptera: Formicidae). Part 1., J. N. Y. Ent. Soc. 66: 118.

    Google Scholar 

  • Buschinger, A., 1972, Giftdrusensekretals Sexualpheromon bei der Ameise Harpogoxenus sublaevis, Naturwissenschaften 59: 313.

    Article  PubMed  CAS  Google Scholar 

  • Buschinger, A., 1976, Giftdrusensekretals Sexualpheromon bei der Gastameise Formicoxenus nitidulus (NYL) (Hym., Form.), Insectes Sociaux 23: 215.

    Article  Google Scholar 

  • Caro, M. R., Derbes, B. J., and Jung, R., 1957, Skin responses to the sting of the imported fire ant (Solenopsis saevissima), Arch. Dermatol. 75: 475.

    Article  CAS  Google Scholar 

  • Cavill, G. W. K., Robertson, P. L., and Whitfield, F. B., 1964, Venom and venom apparatus of the bull ant, Myrmecia gulosa (Fabr.), Science 146: 79.

    Article  PubMed  CAS  Google Scholar 

  • De la Lande, I. S., Thomas, D. I., and Tyler, M. S., 1963, Pharmacological analysis of the venom of the “bulldog” ant Myrmecia forficata, in: Recent Advances in the Pharmacology of Toxins, Proc. 2nd. Int. Pharm. Meeting, Progue, Vol. 9, p. 71.

    Google Scholar 

  • Edery, H., Ishay, J., Lass, I., and Gitter, S., 1972, Pharmacological activity of Oriental hornet (Vespa oriental is) venom, Toxicon 10: 13.

    Article  PubMed  CAS  Google Scholar 

  • Frontali, N., and Grasso, A., 1964, Separation of three toxicologically different protein components from the venom of the spider Latrodectus tredecimguttatus, Arch. Biochem. Biophys. 106: 213.

    Article  PubMed  CAS  Google Scholar 

  • Grunager, P., Quilico, A., and Pavan, M., 1960, Sul secreto del Formicidae Myrmicaria natalensis Fred. Accad. Nazion. Lincei 28: 293.

    Google Scholar 

  • Hermann, H. R., and Blum, M. S., 1966, The morphology and histology of the hymenopterous poison apparatus. I. Paraponera clavata (Formicidae), Ann, ent. Soc. Am. 59: 397.

    Google Scholar 

  • Hermann, H. R., and Blum, M. S., 1967a, The morphology and histology of the hymenopterous poison apparatus. II. Pogonomyrmex badius (Formicidae), Ann, ent. Soc. Am. 60: 661.

    Google Scholar 

  • Hermann, H. R., and Blum, M. S., 1967b, The morphology and histology of the hymenopterous poison apparatus III. Eciton hamatum (Formicidae), Ann, ent. Soc. Am. 60: 1282.

    Google Scholar 

  • Hermann, H. R., and Blum, M. S., 1968, The hymenopterous poison apparatus. VI. Campanotus pennsylvanicus (Hymenoptera: Formicidae), Psyche 75: 215.

    Article  Google Scholar 

  • Higginbotham, R. D., 1965, Mast cells and local resistance to Russell’s viper venom. Immunol. 95: 867.

    CAS  Google Scholar 

  • Holldobler, B., 1971, Sex pheromone in the ant Xenomyrmex floridanus, J. Insect Physiol. 17: 1497.

    Article  Google Scholar 

  • Jentsch, J., 1969, A procedure for purification of Myrmica venom: the isolation of the convulsive component, Proc. VI Congr. IUSSI, Bern, p. 69.

    Google Scholar 

  • Jouvanez, D. P., Blum, M. S., and MacConnell, J. G., 1972, Antibacterial activity of venom alkaloids from the imported fire ant, Solenopsisinvicta Buren, Antimicrob. Ag. Chemotherap. 2: 291.

    Google Scholar 

  • Law, J. H., Wilson, E. O., and McCloskey, J. A., 1965, Biochemical polymorphism in ants, Science 149: 544.

    Article  PubMed  CAS  Google Scholar 

  • Lewis, J. C., and De la Lande, I. S., 1967, Pharmacological and enzymic constituents of the venom of an Australian “bulldog” ant Myrmecia pyriformis, Toxicon 4: 223.

    Article  Google Scholar 

  • Lewis, J. C., Day, A. J., and De la Lande, I. S., 1968, Phospholipase A in the venom of the Australian bulldog ant Myrmecia pyriformis, Toxicon 6: 109.

    Article  PubMed  CAS  Google Scholar 

  • Lockey, R. M., 1974, Systemic reactions to stinging ants, J. Allergy clin. Immunol. 54. 132–146.

    Article  PubMed  CAS  Google Scholar 

  • MacConnell, J. G., Williams, R. N., Brand, J. Fl., and Blum, M. S., 1974, New alkaloids in the venoms of fire ants, Ann, ent. Soc. Am. 67: 134.

    CAS  Google Scholar 

  • Malyshev, S. I., 1968, Genesis of the Hymenoptera and the Phases of their Evolution, Methuen, London.

    Google Scholar 

  • Maschwitz, U. W. J., and Kloft, W., 1971, Morphology and function of the venom apparatus of insects — bees, wasps, ants, and caterpillars, in: Venomous Animals and their Venoms, Vol. 3, ( W. Bücherl and E. E. Buckley, eds) pp 1–60, Academic Press, New York.

    Google Scholar 

  • McCook, H. C., 1879, The Natural History of the Agricultural Ant of Texas, Lippincott’s Press, Philadelphia.

    Google Scholar 

  • McCrone, J. D., 1964, Comparative lethality of several Latrodectus venoms, Toxicon 2: 201.

    Article  CAS  Google Scholar 

  • Neumann, W., and Habermann, E., 1954, Beitrage zur Characterisierung der Wirkstoffe des Bienengiftes, Arch, exp. Path. Pharmakol. 222: 367.

    CAS  Google Scholar 

  • Oeser, R., 1961, Vergleichend Morphologische Untersuchungen über den Ovipositor der Hymenopteran, Mitt. Zool. Mus. Berlin 37: 1.

    Google Scholar 

  • Osman, M. F. H., and Brander, J., 1961, Weitere Beitrage zur Kenntnis der chemischen Zusammensetzung des Giftes von Amiesen aus der Gattung Formica, Z. Naturforsch. 16b: 749.

    Google Scholar 

  • Pedder, D. J., Fales, H. M., Jaouni, T., Blum, M., MacConnell, J. G., and Crewe, R. M., 1976, Constituents of the venom of a South African fire ant (Solenopsis punctaticeps), 2,5-dialkylpyrrolidines and -pyrrolines, identification and synthesis, Tetrahedron 32: 2275.

    Article  CAS  Google Scholar 

  • Pinnas, J. L., Wang, T. M., Strunk, R. C., and Thompson, H. C., 1975, Harvester ant hypersensitivity in vitro and in vivo studies, J. Allerg, clin. Immunol. 55: 107.

    Google Scholar 

  • Regnier, F. E., and Wilson, E. O., 1968, The alarm-defensive system of the ant Acanthomyops claviger, J. Insect Physiol. 14: 953.

    Article  Google Scholar 

  • Ritter, F. J., and Persoons, C. J., 1975, Recent development in insect pheromone research, in particular in the Metherlands, Neth. J. Zool. 25: 261.

    Article  CAS  Google Scholar 

  • Ritter, F. J., Rotgans, I. E. M., Talman, E., Verwiel, P. E. J., and Stein, F., 1973, 5-Methyl-3-butyl-octahydroindolizine, a novel type of pheromone attractive to Pharoah’s ants (Monomorium pharaonis (L.)), Experimentia 29: 530.

    Google Scholar 

  • Schreuder, G. D., and Brand, J. M., 1972, The chemistry of the Dufour’s gland and the poison gland secretions of Anoplolepis custodiens (Hymenoptera: Formicidae), J. Georgia ent. Soc. 7: 188.

    Google Scholar 

  • Stahnke, H. L., 1963, Some pharmacological and biochemical characteristics of Centruroides sculpturatus Ewing scorpion venom, in: Recent Advances in the Pharmacology of Toxins, Vol. 9, (H. W. Raudonat and J. Vanecek, eds), ppT 63–70, MacMillan, New York.

    Google Scholar 

  • Stumper, R., 1922, Nouvelles observations sur le venin des fourmis, C. R. Acad. Sci. 174: 66.

    CAS  Google Scholar 

  • Stumper, R. 1952, Données quantitatives sur la sécrétion d’acide formique par les fourmis, C. R. Acad. Sci. 234: 149.

    CAS  Google Scholar 

  • Stumper, R., 1960, Die Giftsekretion der Ameisen, Naturwissenschaften 47: 457.

    Article  Google Scholar 

  • Talman, E., Ritter, F. J., and Verwiel, P. E. J., 1974, Structure elucidation of pheromones produced by the Pharoah’s ant, Monomorium pharaonis L. in: Proceedings International Symposium on Mass Spectrometry in Biochemistry and Medicine, Milan, 1973, Raven Press, New York.

    Google Scholar 

  • Thomas, D. W., and Lewis, J. C., 1965, Histamine released by the ant, Aust. J. exp. Biol. med. Sci. 43; 275.

    Google Scholar 

  • Tumlinson, J. H., Silverstein, R. M., Moser, J. C., Brownleee, R. G., and Ruth, J. M., 1971, Identification of the trail pheromone of a leaf-cutting ant, Atta texana, Nature 234: 348.

    Article  PubMed  CAS  Google Scholar 

  • Wanstall, J. C., and De la Lande, I. S., 1974, Fractionation of bulldog ant venom, Toxicon 12: 649.

    Article  PubMed  CAS  Google Scholar 

  • Weber, N., 1959, The stings of the harvesting ant, Pogonomyrmex occidental is (Cresson), with a note on populations (Hymenoptera), Ent. News 70: 85.

    Google Scholar 

  • Williams, M. W., and Williams, C. S., 1964, Collection and toxicity studies of ant venom, Proc. Soc. exp. Biol. Med. 116: 161.

    PubMed  CAS  Google Scholar 

  • Williams, M. W., and Williams, C. S., 1965, Toxicity of ant venom, further studies of the venom from Pogonomyrmex barbatus, Proc. Soc. exp. Biol. Med. 119: 344.

    PubMed  CAS  Google Scholar 

  • Wilson, E. O., Carpenter, F. M., and Brown, W. L., Jr., 1967, The mesozoic ants, with the description of a new subfamily, Psyche 74: 1.

    Article  Google Scholar 

  • Wray, J., 1670, Some uncommon observations and experiments made with an acid juyce to be found in ants. Phil. Trans. Roy. Soc. London 1670: 2063.

    Google Scholar 

  • Yeh, J. Z., Narahashi, T., and Almon, R. L., 1975, Characterization of neuromuscular blocking action of piperidine derivatives, J. Pharmac. exp. Therap. 194: 373.

    CAS  Google Scholar 

  • Zlotkin, E., Rochat, H., Kopeyan, C., Miranda, F., and Lissitzky, S., 1971, Purification and properties of the insect toxin from the venom of the scorpion Androctonus austral is Hector, Biochimie 53: 1073.

    Article  PubMed  CAS  Google Scholar 

  • Zlotkin, E., Rathmayer, W., and Lissitzky S., 1978, Chemistry specificity and action of arthropod toxic proteins derived from scorpion venoms, in: Pesticide and Venom Neurotoxicity (D.L. Shankland, R.M. Hoi 1ingworth, and T. Smyth, Jr., eds.) Plenum Press, New York, pp. 227–246.

    Chapter  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1978 Plenum Press, New York

About this chapter

Cite this chapter

Schmidt, J.O. (1978). Ant Venoms: A Study of Venom Diversity. In: Shankland, D.L., Hollingworth, R.M., Smyth, T. (eds) Pesticide and Venom Neurotoxicity. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8834-4_20

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-8834-4_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-8836-8

  • Online ISBN: 978-1-4615-8834-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics