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Neurophysiological Study of the Structure-Activity Relations of Insecticides

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Pesticide and Venom Neurotoxicity

Abstract

Structure-activity relationships of insecticides have been a subject of investigations for many years since the development of synthetic insecticides such as DDT and organophosphates. In most cases, these studies were based on the comparison of insect killing potencies of a variety of analogs and derivatives of a parent compound. However, since the action of an insecticide in killing insects is exerted as a result of a chain of reactions, it is difficult to relate such killing potencies to the chemical structures of the insecticide. The process of toxic action of an insecticide is summarized as follows.

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© 1978 Plenum Press, New York

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Narahashi, T. (1978). Neurophysiological Study of the Structure-Activity Relations of Insecticides. In: Shankland, D.L., Hollingworth, R.M., Smyth, T. (eds) Pesticide and Venom Neurotoxicity. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8834-4_10

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  • DOI: https://doi.org/10.1007/978-1-4615-8834-4_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-8836-8

  • Online ISBN: 978-1-4615-8834-4

  • eBook Packages: Springer Book Archive

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