Abstract
The problem of defining sleep in biochemical terms is extraordinarily difficult, yet studies in this area are numerous and have a long history. Many of them focus on the general metabolism of the sleeping animal compared with the waking animal. They provide observations often really only peripheral to the central question: what biochemical manifestations are intrinsically causative of, or directly the result of, sleep?
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References
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Karnovsky, M.L., Reich, P. (1977). Biochemistry of Sleep. In: Agranoff, B.W., Aprison, M.H. (eds) Advances in Neurochemistry. Advances in Neurochemistry, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8237-3_4
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