Abstract
Five human muscarinic acetylcholine receptors (mAChR) (ml–m5), have been cloned and expressed in suitable cell systems (reviewed by Hulme et al., 1990). * mAChRs have two binding domains, a ligand-binding extracellular (and including membrane-spanning) domain and a G-protein binding intracellular domain. This second domain, by interaction with various G-proteins, controls and modulates second messenger systems (Hulme et al., 1990).
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© 1994 Birkhäuser Boston
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Fisher, A. et al. (1994). Selective Signaling Via Novel Muscarinic Agonists: Implications for Alzheimer’s Disease Treatments and Clinical Update. In: Giacobini, E., Becker, R.E. (eds) Alzheimer Disease. Advances in Alzheimer Disease Therapy. Birkhäuser Boston. https://doi.org/10.1007/978-1-4615-8149-9_37
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DOI: https://doi.org/10.1007/978-1-4615-8149-9_37
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