Vasopressin pp 211-256 | Cite as

Electrophysiology of the Central Vasopressin System

  • J. B. Wakerley


The goal of the electrophysiologist working on the central vasopressin (VP) system is to provide a complete description of all electrical events intervening between arrival of synaptic transmitters or other agents on the membrane receptors of the VP-secreting neurosecretory cells and of activation of the exocytotic process leading to VP release from the neurohypophysial terminals. On a wider scale, the electrophysiologist may endeavor to describe the generation and integration of nerve impulses within the various afferent pathways impinging upon VP cells. Armed with such information, the electrophysiologist can then hope to provide a complete explanation of how stimuli that influence VP release are integrated and processed to bring about a particular level and pattern of hormonal output. As will become apparent, the past decade has seen considerable advance toward the attainment of this objective.


Firing Pattern Supraoptic Nucleus Magnocellular Nucleus Hypothalamic Slice Antidromic Action Potential 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • J. B. Wakerley
    • 1
  1. 1.Department of Anatomy, The Medical SchoolUniversity of BristolBristolEngland

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