Abstract
The biogenesis of ribosomes in eukaryotes involves the generation in the cell of the constituent core rRNA molecules and their interaction with about 80 distinct proteins to form the two mature ribosomal particles. Therefore, the ribosome is not only the principal organelle in gene expression, but it is also one of the best-understood models of the structure, function, and coordination of a large number of genes operating in the eukaryotic cell. Furthermore, ribosomes are made in the nucleolus, but they operate in the cytoplasm. In this respect, studies on the biogenesis of ribosomes contribute to our understanding of the molecular architecture of the cell.
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References
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Hadjiolov, A.A. (1980). Biogenesis of Ribosomes in Eukaryotes. In: Roodyn, D.B. (eds) Subcellular Biochemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7948-9_1
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