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Structure and Function of the Circulation pp 357–399Cite as

Differentiation and Phenotypic Modulation of Arterial Smooth Muscle Cells

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Abstract

The process of differentiation of a cell involves its transformation from an initially totipotential cell to the specialized form of the adult as occurs, for instance, in normal development. A fully differentiated cell is one, therefore, which has lost all potentiality to develop into another cell type.

This work was supported by grants from the National Heart Foundation of Australia, Life Insurance Medical Research Fund of Australia and New Zealand, and the National Health and Medical Research Council of Australia.

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Authors and Affiliations

  1. Department of Anatomy, University of Melbourne, Parkville, 3052, Victoria, Australia

    G. R. Campbell Ph.D.

  2. Baker Medical Research Institute, Commercial Road, Prahran, 3181, Victoria, Australia

    J. H. Chamley-Campbell Ph.D.

  3. Department of Anatomy and Embryology, University College, London, England

    G. Burnstock D.Sc, F.A.A.

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  1. G. R. Campbell Ph.D.
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Editors and Affiliations

  1. University of Texas Health Science Center, USA

    Colin J. Schwartz M.D., F.R.A.C.P. (Professor of Pathology, Member of Scientific Staff) (Professor of Pathology, Member of Scientific Staff)

  2. Southwest Foundation for Research & Education, San Antonio, Texas, USA

    Colin J. Schwartz M.D., F.R.A.C.P. (Professor of Pathology, Member of Scientific Staff) (Professor of Pathology, Member of Scientific Staff)

  3. Office of Naval Research, Boston, Massachusetts, USA

    Nicholas T. Werthessen Ph.D. (Bioscientist, Senior Research Associate) (Bioscientist, Senior Research Associate)

  4. Brown University, Providence, Rhode Island, USA

    Nicholas T. Werthessen Ph.D. (Bioscientist, Senior Research Associate) (Bioscientist, Senior Research Associate)

  5. Medical Affairs, St. Luke’s Hospital, Bethlehem, Pennsylvania, USA

    Stewart Wolf M.D. (Vice President, Professor of Medicine, Director) (Vice President, Professor of Medicine, Director)

  6. Temple University, Philadelphia, Pennsylvania, USA

    Stewart Wolf M.D. (Vice President, Professor of Medicine, Director) (Vice President, Professor of Medicine, Director)

  7. Totts Gap Institute, Bangor, Pennsylvania, USA

    Stewart Wolf M.D. (Vice President, Professor of Medicine, Director) (Vice President, Professor of Medicine, Director)

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Campbell, G.R., Chamley-Campbell, J.H., Burnstock, G. (1981). Differentiation and Phenotypic Modulation of Arterial Smooth Muscle Cells. In: Schwartz, C.J., Werthessen, N.T., Wolf, S. (eds) Structure and Function of the Circulation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7927-4_6

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