Abstract
Air pollutants in the form of particles, gases, or vapors can exist in the occupational setting or in a defined environment. Such pollutants can be caused by the end products, by-products, or materials used in industrial processes. If any of the pollutants are mutagenic, they may pose carcinogenic and genotoxic hazards to the exposed population. Mutagenic monitoring of the workplace environment can be used to determine whether workers are being exposed to mutagenic and potentially carcinogenic compounds. The results of mutagenic monitoring studies can be used to guide human genetic monitoring, epidemiology, and industrial hygiene studies. Efforts can be made immediately to reduce the exposure of workers to mutagenic compounds on a generic control basis.
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References
Ames, B.N., J. McCann, and E. Yamasaki. 1975. Method for detecting carcinogens and mutagens with the Salmonella/mammaiian-microsome mutagenicity test. Mutat. Res. 31:347–364.
Goto, K., S. Maeda, Y. Kano, and T. Sugiyama. 1978. Factors involved in differential Giemsa-staining of sister chromatids. Chromosoma 66:351–359.
Lower, W.R. 1981. Mutagenic effects of petro chemical complexes onZea mays, Tradescantia, and Salmonella. Environ. Mutagen. 3:400.
Ma, T-H. 1982. Tradescantia cytogenetic tests (root-tip mitosis, pollen mitosis, pollen mother-cell meiosis): A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res. 99:293–302.
Ong, T., J. Stewart, and W-Z. Whong. 1984. A simple in situ mutagenicity test system for detection of mutagenic air pollutants. Mutat. Res. 139:177–181.
Perry, P., and S. Wolff. 1974. New Giemsa method for the differential staining of sister chromatids. Nature 251:156–158.
Plewa, M.J. 1982. Specific-locus mutation assay in Zea mays: A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res. 99:317–337.
Schairer, L.A., J. Van’t Hof, C.G. Hayes, R.M. Burton, and F.J. de Serres. 1978. Exploratory monitoring of air pollutants for mutagenicity activity with the Tradescantia stamen hair system. Environ. Health Perspect. 27:51–60.
Vogel, H.J., and D M. Bonner. 1956. Acetylornithinase of E. coli, partial purification and some properties. J. Biol Chem. 218:97–106.
Whong, W-Z., J.D. Stewart, and T. Ong. 1984. Development of an in situ microbial mutagenicity test system for airborne workplace mutagens: Laboratory evaluation. Mutat. Res. 130:45–51.
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© 1985 Springer Science+Business Media New York
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Ong, Tm., Stewart, J.D., Tucker, J.D., Whong, WZ. (1985). Development of an In Situ Test System for Detection of Mutagens in the Workplace. In: Waters, M.D., Sandhu, S.S., Lewtas, J., Claxton, L., Strauss, G., Nesnow, S. (eds) Short-Term Bioassays in the Analysis of Complex Environmental Mixtures IV. Environmental Science Research, vol 32. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7849-9_3
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DOI: https://doi.org/10.1007/978-1-4615-7849-9_3
Publisher Name: Springer, Boston, MA
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