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Human Cytogenetic Monitoring: Occupational Exposure to Ethylene Oxide

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Book cover Short-Term Bioassays in the Analysis of Complex Environmental Mixtures IV

Part of the book series: Environmental Science Research ((ESRH,volume 32))

Abstract

Concern about environmental/occupational exposure to DNA-damaging agents has led to widespread interest in establishing reliable methods to monitor potentially exposed people. Measurement of damage to chromosomes in blood lymphocytes is one of the few monitoring methods available and can be a useful biological dosimeter. Although the health risks associated with chromosome damage are not known, it is possible that exposure to DNA-damaging agents may increase the occurrence of cancer and of heritable genetic changes in the population.

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Author notes

  1. S. M. Galloway & W. W. Nichols

    Present address: Merck Institute for Therapeutic Research, 19486, West Point, Pennsylvania, USA

Authors and Affiliations

  1. Litton Bionetics, Inc., 20895, Kensington, Maryland, UK

    S. M. Galloway & P. K. Berry

  2. Institute for Medical Research, 08103, Camden, New Jersey, USA

    W. W. Nichols

  3. Department of Pathology, New York University School of Medicine, 10016, New York, New York, USA

    S. R. Wolman

  4. Clinical Epidemiology Unit, Department of Medicine, University of Pennsylvania Medical School, 19104, Philadelphia, Pennsylvania, USA

    K. A. Soper & P. D. Stolley

Authors
  1. S. M. Galloway
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  2. P. K. Berry
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  3. W. W. Nichols
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  4. S. R. Wolman
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  5. K. A. Soper
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  6. P. D. Stolley
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Editors and Affiliations

  1. U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA

    Michael D. Waters , Shahbeg S. Sandhu , Joellen Lewtas , Larry Claxton , Gary Strauss  & Stephen Nesnow , , , ,  & 

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Galloway, S.M., Berry, P.K., Nichols, W.W., Wolman, S.R., Soper, K.A., Stolley, P.D. (1985). Human Cytogenetic Monitoring: Occupational Exposure to Ethylene Oxide. In: Waters, M.D., Sandhu, S.S., Lewtas, J., Claxton, L., Strauss, G., Nesnow, S. (eds) Short-Term Bioassays in the Analysis of Complex Environmental Mixtures IV. Environmental Science Research, vol 32. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7849-9_24

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  • DOI: https://doi.org/10.1007/978-1-4615-7849-9_24

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-7851-2

  • Online ISBN: 978-1-4615-7849-9

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