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Recovery after Brain Damage and the Concept of Localization of Function

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Recovery from Brain Damage

Abstract

Although damage to the central nervous system often results in permanent disruption or loss of behavioral function, a remarkable degree of recovery or restitution may occur under certain circumstances. In some cases, there is a return to normal or near-normal levels of performance even after extensive loss of nervous tissue. However, there is considerable disagreement over the nature of, and reasons for, such recovery and consequently over its meaning for our understanding of nervous system organization and activity in the intact organism. There seem to be at least two principal reasons for the lack of a unitary approach to recovery of function. First, varying methodologies and the large number of complex and interdependent factors which influence recovery of function often prevent any one specialist from making meaningful generalization of findings to areas removed from his or her immediate area of inquiry. Second is the confusion generated by the ambiguous and sometimes meaningless nature of the terms and concepts used to describe and interpret the operations of the nervous system and the mechanisms thought to subserve restitution of function after damage.

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References

  • Adametz, J. H. Rate of recovery of functioning in cats with rostral reticular lesions. Journal of Neurosurgery, 1959, 16, 85–98.

    Article  PubMed  Google Scholar 

  • Beach, F., Hebb, D., Morgan, C., and Nissen, H. (Eds.) The neuropsychology of Lashley: selected papers. New York: McGraw-Hill, 1960.

    Google Scholar 

  • Bekoff, M., Lockwood, A., and Meikle, T. H., Jr. Effects of serial lesions in cat visual cortex on a brightness discrimination. Brain Research, 1972, 48, 219–220.

    Google Scholar 

  • Berger, B. D., Wise, C. D., and Stein, L. Norepinephrine: Reversal of anorexia in rats with lateral hypothalamic damage. Science, 1971, 172, 281–284.

    Article  PubMed  Google Scholar 

  • Bernard, C. Introduction à l’étude de la médécine expérimentale, 1865, Paris. Reissued Paris: Garnier-Flammarion, 1966.

    Google Scholar 

  • Bernstein, J. J., and Bernstein, M. E. Neuronal alteration and reinnervation following ax-onal regeneration and sprouting in mammalian spinal cord. In J. J. Bernstein and D. C. Goodman (Eds.), Neuromorphological plasticity. Basel: S. Karger, 1973, pp. 135–161.

    Google Scholar 

  • Bernstein, J. J., and Goodman, D. C. Overview. Brain, Behavior and Evolution, 1973, 8, 162–164.

    Article  Google Scholar 

  • Bizzi, E., and Evarts, E. V. Translational mechanisms between input and output. Neurosciences Research Program Bulletin, 1971, 9, 31–59.

    PubMed  Google Scholar 

  • Björklund, A., Johansson, B., Stenevi, U., and Svengaard, N. Re-establishment of functional connections by regenerating central adrenergic and cholinergic axons. Nature, 1975, 253, 446–448.

    Article  PubMed  Google Scholar 

  • Burke, R. E. Control systems operating on spinal reflex mechanisms. Neurosciences Research Program Bulletin, 1971, 9, 60–85.

    PubMed  Google Scholar 

  • Butters, N., Butter, C., Rosen, J., and Stein, D. G. Behavioral effects of sequential and one-stage ablations of orbital prefrontal cortex in the monkey. Experimental Neurology, 1973, 39, 204–214.

    Article  PubMed  Google Scholar 

  • Chambers, W. E., Liu, C. N., and McCouch, G. P. Anatomical and physiological correlates of plasticity in the central nervous system. Brain, Behavior and Evolution, 1973, 8, 5–26.

    Article  PubMed  Google Scholar 

  • Chow, K. L. Effects of ablation. In G. C. Quarton, M. Melnechuk, and F. O. Schmitt, (Eds.), The neurosciences, first study program. New York: Rockefeller University Press, 1967, pp. 705–713.

    Google Scholar 

  • Clark, S. M., Meyer, P. M., Meyer, D. R., and Yutzey, D. A. Emotionality changes following septal and neocortical ablations in the albino rat. Psychon. Science, 1967, 8, 125–126.

    Google Scholar 

  • Cowan, W. M. Neuronal death as a regulative mechanism in the control of cell number in the nervous system. In M. Rockstein (Ed.), Development and aging in the nervous system. New York: Academic Press, 1973, pp. 19–42.

    Google Scholar 

  • Cytawa, J., and Teitelbaum, P. Spreading depression and recovery of subcortical functions. Acta Biologica Experimentalis, 1967, 27, 345–353.

    Google Scholar 

  • Dawson, R. G. Recovery of function: Implications for theories of brain function. Behavioral Biology, 1973, 8, 439–460.

    Article  PubMed  Google Scholar 

  • Eidelberg, E., Kreinick, C. J., and Langescheid, C. On the possible functional role of afferent pathways in skin sensation. Experimental Neurology, 1975, 47, 419–432.

    Article  PubMed  Google Scholar 

  • Falck, B. Observations on the possibilities of the cellular localization of monoamines by a flourescence method. ACTA Physiologica Scandanavica, 1962, 56:Suppl. 197, 1–25.

    Google Scholar 

  • Fass, B., Jordan, H., Rubman, A., Seibel, S., and Stein, D. G. Recovery of function after serial or one-stage lesions of the lateral hypothalamic area in rats. Behavioral Biology, 1975, 14, 283–294.

    Article  PubMed  Google Scholar 

  • Galambos, R., Norton, T. T., and Frommer, C. P. Optic tract lesions sparing pattern vision in cats. Experimental Neurology, 1967, 18, 8–25.

    Article  PubMed  Google Scholar 

  • Gazzaniga, M. S. Eye position and visual motor coordination. Neuropsychologia, 1969a, 7, 379–382.

    Google Scholar 

  • Gazzaniga, M. S. Cross-cuing mechanisms and ipsilateral eye-hand control in split brain monkeys. Experimental Neurology, 1969b, 23, 11–17.

    Article  PubMed  Google Scholar 

  • Gazzaniga, M. Determinants of cerebral recovery. In D. G. Stein, J. J. Rosen, and N. Butters (Eds.), Plasticity and recovery of function in the central nervous system. New York: Academic Press, 1974, pp. 203–216.

    Google Scholar 

  • Gentile, A., Schmelzer, W., Green, S., Nieburgs, A., and Stein, D. G. Disruption and recovery of locomotion and manipulation following cortical lesions in rats. Behavioral Biology, in press.

    Google Scholar 

  • Geschwind, N. Late changes in the nervous system: An overview. In D. G. Stein, J. J. Rosen, and N. Butters (Eds.), Plasticity and recovery of function in the central nervous system. New York: Academic Press, 1974, pp. 467–508.

    Google Scholar 

  • Glassman, R. B. Contralateral and ipsilateral transfer of a cutaneous discrimination in normal and callosum-sectioned cats. Journal of Comparative and Physiological Psychology, 1970, 70, 470–475.

    Article  PubMed  Google Scholar 

  • Glick, S. D. Changes in drug sensitivity and mechanisms of functional recovery following brain damage. In D. G. Stein, J. J. Rosen, and N. Butters (Eds.), Plasticity and recovery of function in the central nervous system. New York: Academic Press, 1974, pp. 339–374.

    Google Scholar 

  • Glick, S. D., and Greenstein, S. Possible modulating influence of frontal cortex on nigrostriatal function. British Journal of Pharmacology, 1973a, 49, 316–321.

    PubMed  Google Scholar 

  • Glick, S. D., and Greenstein, S. Recovery of weight regulation following ablation of frontal cortex in rats. Physiology and Behavior, 1973b, 10, 491–496.

    Article  PubMed  Google Scholar 

  • Glick, S. D., and Zimmerberg, B. Comparative recovery following simultaneous and successive-stage frontal brain damage in mice. Journal of Comparative and Physiological Psychology, 1972, 79, 481–487.

    Article  PubMed  Google Scholar 

  • Goldberger, M. E. Restitution of function in the CNS: The pathologic grasp in macaca mulatta. Experimental Brain Research, 1972, 15, 79–96.

    Article  Google Scholar 

  • Goldberger, M. E. Recovery of movement after CNS lesions in monkeys. In D. G. Stein, J. J. Rosen, and N. Butters (Eds.), Plasticity and recovery of function in the central nervous system. New York: Academic Press, 1974, pp. 265–337.

    Google Scholar 

  • Goldman, P. S. Developmental determinants of cortical plasticity. ACTA Neurobiologiae Experimentalis, 1972, 32, 495–511.

    PubMed  Google Scholar 

  • Goldman, P. An alternative to developmental plasticity: Heterology of CNS structures in infants and adults. In D. G. Stein, J. J. Rosen, and N. Butters (Eds.), Plasticity and recovery of function in the central nervous system. New York: Academic Press, 1974, pp. 149–174.

    Google Scholar 

  • Goldman, P. Age, sex, and experience as related to the neural basis of cognitive development. In N. A. Buchwald and M. A. B. Brazier (Eds.), Brain mechanisms in mental retardation. New York: Academic Press, 1975, pp. 379–389.

    Google Scholar 

  • Goodman, D. C., and Horel, J. A. Sprouting of optic tract projections in the brain stem of the rat. Journal of Comparative Neurology, 1966, 127, 71–88.

    Article  PubMed  Google Scholar 

  • Goodman, D. C., Bogdasarian, R. S., and Horel, J. A. Axonal sprouting of ipsilateral optic tract following opposite eye removal. Brain, Behavior and Evolution, 1973, 8, 27–50.

    Article  PubMed  Google Scholar 

  • Greenough, W. T., Fass, B., and deVoogd, T. The influence of experience on recovery following brain damage in rodents: Hypotheses based on development research. In R. N. Walsh and W. T. Greenough (Eds.), Environments as therapy for brain dysfunction. New York: Plenum Press, 1976.

    Google Scholar 

  • Grossman, S. P. Direct adrenergic and cholinergic stimulation of hypothalamic mechanisms. American Journal of Physiology, 1962, 202, 872–882.

    PubMed  Google Scholar 

  • Hecaen, H. Aphasie, apraxic and agnosic syndromes in right and left hemisphere lesions. In P. J. Vinken and G. W. Bruyn (Eds.), Handbook of clinical neurology. Vol. 4. Amsterdam: North Holland Publishing Company, 1969, pp. 176–179, 391–411.

    Google Scholar 

  • Hicks, S. P., and d’ Amato, C. J. Motor-sensory cortex-corticospinal system and developing locomotion and placing in rats. American Journal of Anatomy, 1975, 143, 1–42.

    Article  PubMed  Google Scholar 

  • Horel, J. A., Bettinger, L. A., Royce, G. J., and Meyer, D. R. Role of neo-cortex in the learning and re-learning of two visual habits by the rat. Journal of Comparative and Physiological Psychology, 1966, 61, 66–78.

    Article  PubMed  Google Scholar 

  • Isaacson, R. L. The myth of recovery from early brain damage. In N. R. Ellis, (Ed.) Aberrant development in infancy. Potomac, Md.: Lawrence Erlbaum, 1975.

    Google Scholar 

  • Isseroff, A., Leveton, L., Freeman, G., Lewis, M., and Stein, D. G. The limits of behavioral recovery from serial lesions of the hippocampus. Experimental Neurology, 1976, 53, 339–354.

    Article  PubMed  Google Scholar 

  • Jackson, J. H. Remarks on the diagnosis and treatment of diseases of the brain. British Medical Journal, 1888, 2, 59–63.

    Article  PubMed  Google Scholar 

  • Kennard, M. A. Reorganization of motor function in the cerebral cortex of monkeys deprived of motor and premotor areas in infancy. Journal of Neurophysiology, 1938, 1, 477–496.

    Google Scholar 

  • Kleiner, F. B., Meyer, P. M., and Meyer, D. R. Effects of simultaneous septal and amygdaloid lesions upon emotionality and retention of a black-white discrimination. British Research, 1967, 5, 459–468.

    Article  Google Scholar 

  • Lashley, K. S. Brain mechanisms and intelligence. Chicago: University of Chicago Press, 1929.

    Google Scholar 

  • LeVere, T. E. Neural stability, sparing and behavioral recovery following brain damage. Psychological Review, 1975, 82, 344–358.

    Article  PubMed  Google Scholar 

  • Lund, R. D., and Lund, J. S. Synaptic adjustment after deafferentation of the superior colliculus of the rat. Science, 1971, 171, 804–807.

    Article  PubMed  Google Scholar 

  • Luria, A. R. Restoration of brain function after war injuries. Izd. Acad. Med. Nauk. SSSR (Moscow), 1948.

    Google Scholar 

  • Luria, A. R., Naydin, V. L., Tsvetkova, L. S., and Vinarskaya, E. N. Handbook of clinical neurology: disorders of the higher nervous system. Vol. III. North Holland, American Elsevier, 1969, pp. 368–433.

    Google Scholar 

  • Lynch, G., Matthews, D. A., Mosko, S., Parks, T., and Cotman, C. Induced acetylcholinesterase-rich layer in rat dentate gyrus following entorhinal lesions. Brain Research, 1972,42, 311–318.

    Article  PubMed  Google Scholar 

  • Margules, D. L., Lewis, M. J., Dragovich, J. A., and Margules, A. S. Hypothalamic norepinephrine: circadian rhythms and the control of feeding behavior. Science, 1972, 178, 640–642.

    Article  PubMed  Google Scholar 

  • Merrill, E. G., and Wall, P. D. Factors forming the edge of a receptive field: The presence of relatively ineffective afferent terminals. Journal of Physiology (London), 1972, 226, 825–846.

    Google Scholar 

  • Meyer, D. R., Harlow, H. F., and Ades, H. W. Retention of delayed responses and proficiency in oddity problems by monkeys with preoccipital ablations. American Journal of Psychology, 1951, 64, 391–396.

    Article  PubMed  Google Scholar 

  • Meyer, P. M. Recovery from neo-cortical damage. In G. French (Ed.), Cortical functioning in behavior. Glenview, Ill.: Scott, Foresman, 1973, pp. 115–138.

    Google Scholar 

  • Milner, B. Sparing of language functions after early unilateral brain damage. In E. Eidelberg and D. G. Stein, Functional recovery after lesions of the nervous system. Neurosciences Research Program Bulletin, 1974, 12, 213–216.

    PubMed  Google Scholar 

  • Moore, R. Y. Central regeneration and recovery of function: The problem of collateral reinnervation. In D. G. Stein, J. J. Rosen, and N. Butters (Eds.), Plasticity and recovery of function in the central nervous system. New York: Academic Press, 1974, pp. 111–128.

    Google Scholar 

  • Moore, R. Y., Björklund, A., and Stenevi, U. Plastic changes in the adrenergic innervation of the rat septal area in response to denervation. Brain Research, 1971, 33, 13–35.

    Article  PubMed  Google Scholar 

  • Nauta, W. H.J. M. The problem of the frontal lobe: A reinterpretation. Journal of Psychiatric Research, 1971, 8, 167–187.

    Article  PubMed  Google Scholar 

  • Pasik, P., Pasik, T., and Schilder, P. Extrageniculostriate vision in the monkey: discrimination of luminous flux-equated figures. Experimental Neurology, 1969, 24, 421–437.

    Article  PubMed  Google Scholar 

  • Pribram, K. H. Languages of the brain: Experimental paradoxes and principles in neuropsychology. Englewood Cliffs, N.J.: Prentice-Hall, 1971.

    Google Scholar 

  • Prince, M. Cerebral localization from the point of view of function and symptoms. Journal of Nervous and Mental Diseases, 1910, 37, 337–354.

    Article  Google Scholar 

  • Raisman, G. Neuronal plasticity in the septal nuclei of the adult brain. Brain Research, 1969, 14, 25–48.

    Article  PubMed  Google Scholar 

  • Raisman, G., and Field, P. M. A quantitative investigation of the development of collateral reinnervation after partial deafferentation of the septal nuclei. Brain Research, 1973, 50, 241–264.

    Article  PubMed  Google Scholar 

  • Rakic, R. Timing of major ontogenetic events in the visual cortex of the rhesus monkey. In N. A. Buchwald and M. A. B. Brazier (Eds.), Brain mechanisms in mental retardation. New York: Academic Press, 1975, pp. 3–37.

    Google Scholar 

  • Reitan, R. M. Problems and prospects in studying the psychological correlates of brain lesions. Cortex, 1966, 2, 127–154.

    Google Scholar 

  • Riese, W. Principles of neurology. Nervous and Mental Disease Monographs, 1950, 80, 1–168.

    Google Scholar 

  • Rose, J. E., Malis, L. I., Kruger, L., and Baker, C. P. Effects of heavy ionizing monoenergetic particles on the cerebral cortex. II. Histological appearance of laminar lesions and growth of nerve fibers after laminar destruction. Journal of Comparative Neurology, 1959, 115, 243–297.

    Article  Google Scholar 

  • Rose, J. E., Malis, L. I., and Baker, C. P. Neural growth in the cerebral cortex after lesions produced by monoenergetic deuterons. In W. A. Rosenblith (Ed.), Sensory Communication. Cambridge: M.I.T. Press, 1961.

    Google Scholar 

  • Rosen, J. J., and Stein, D. G. Spontaneous alternation behavior in the rat. Journal of Comparative and Physiological Psychology, 1969, 68, 420–426.

    Article  PubMed  Google Scholar 

  • Rosen, J. J., Stein, D. G., and Butters, N. Recovery of function after serial ablation of prefrontal cortex in the rhesus monkey. Science, 1971, 173, 353–356.

    Article  PubMed  Google Scholar 

  • Rosner, B. S. Brain functions. Annual Review of Psychology, 1970, 21, 555–594.

    Article  PubMed  Google Scholar 

  • Rosner, G. Recovery of function and localization of function in historical perspective. In D. G. Stein, J. J. Rosen, and N. Butters (Eds.), Plasticity and recovery of function in the central nervous system. New York: Academic Press, 1974, pp. 1–30.

    Google Scholar 

  • Schneider, G. E. Early lesions of superior colliculus: factors affecting the formation of abnormal retinal projections. Brain, Behavior and Evolution, 1973, 8, 73–109.

    Article  PubMed  Google Scholar 

  • Schneider, G. E., and Jhavari, S. R. Neuroanatomical correlates of spared or altered function after brain lesions in the newborn hamster. In D. G. Stein, J. J. Rosen, and N. Butters (Eds.), Plasticity and recovery of function in the central nervous system. New York: Academic Press, 1974, pp. 65–110.

    Google Scholar 

  • Schultze, M., and Stein, D. G. Recovery of function in the albino rat following either simultaneous or seriatum lesions of the caudate nucleus. Experimental Neurology, 1975, 46, 291–301.

    Article  PubMed  Google Scholar 

  • Schwartzbaum, J. S., and Gray, P. E. Interacting behavioral effects of septal and amygdaloid lesions in the rat. Journal of Comparative and Physiological Psychology, 1966, 61, 59–65.

    Article  PubMed  Google Scholar 

  • Skolnick, P., and Daly, J. W. Norepinephrine-sensitive adenylate cyclases in rat brain: Relation to behavior and tyrosine hydroxylase. Science, 1974, 184, 175–177.

    Article  PubMed  Google Scholar 

  • Sotelo, C., and Palay, S. L. Altered axons and axon terminals in the lateral vestibular nucleus of the rat: Possible example of neuronal remodeling. Laboratory Investigation, 1971, 25, 653–671.

    PubMed  Google Scholar 

  • Spear, P. D., and Braun, J. J. Pattern discrimination following removal of visual neocortex in the cat. Experimental Neurology, 1969, 25, 331–348.

    Article  PubMed  Google Scholar 

  • Spear, P. S., and Barbas, H. Recovery of pattern discrimination ability in rats receiving serial or one-stage visual cortex lesions. Brain Research, 1975, 94, 337–346.

    Article  PubMed  Google Scholar 

  • Stein, D. G., Rosen, J. J., Graziadei, J., Mishkin, D., and Brink, J. Central nervous system: Recovery of function. Science, 1969, 166, 528–530.

    Article  PubMed  Google Scholar 

  • Stein, D. G. Some variables influencing recovery of function after CNS lesions in the rat. In D. G. Stein, J.J. Rosen, and N. Butters (Eds.), Plasticity and recovery of function in the central nervous system. New York: Academic Press, 1974, pp. 373–427.

    Google Scholar 

  • Stein, D. G., Rosen, J. J., Butters, N. (Eds.), Plasticity and recovery of function in the central nervous system. New York: Academic Press, 1974.

    Google Scholar 

  • Stein, D. G., and Firl, A. Brain damage and reorganization of function in old age. Experimental Neurology, 1976, 52, 157–167.

    Article  Google Scholar 

  • Stenevi, U., Björklund, A., and Moore, R. Y. Growth of intact central adrenergic axons in the denervated lateral geniculate body. Experimental Neurology, 1972, 35, 290–299.

    Article  PubMed  Google Scholar 

  • Stenevi, U., Björklund, A., and Moore, R. Y. Morphological plasticity of central adrenergic neurons. Brain, Behavior and Evolution, 1973, 8, 110–134.

    Article  Google Scholar 

  • Teitelbaum, P. The encephalization of hunger. In E. Steiler and J. M. Sprague (Eds.), Progress in Physiological Psychology. Vol. 4. New York: Academic Press, 1971, pp. 319–346.

    Google Scholar 

  • Teitelbaum, P., and Cytawa, J. Spreading depression and recovery from lateral hypothalamic damage. Science, 1965, 147, 61–63.

    Article  PubMed  Google Scholar 

  • Teitelbaum, P. and Epstein, A. The lateral hypothalamic syndrome: Recovery of feeding and drinking after lateral hypothalamic lesions. Psychological Review, 1962, 69, 74–90.

    Article  PubMed  Google Scholar 

  • Teuber, H. L. Recovery of function after lesions of the central nervous system: History and prospects. In E. Eidelberg and D. G. Stein, Functional recovery after lesions of the nervous system. Vol. 12. Neurosciences Research Program Bulletin, 1974, pp. 197–211.

    Google Scholar 

  • Trendelenburg, U. Supersensitivity and subsensitivity to sympathamimetic amines. Pharmacological Review, 1963, 75, 225–277.

    Google Scholar 

  • Trendelenburg, U. Factors influencing the concentration of catecholamines at the receptors. In H. Blaschko and E. Muscholl (Eds.), Catecholamines: Handbuch der Experimentellen Pharmakologie, XXXIII, Berlin: Springer-Verlag, 1972.

    Google Scholar 

  • Ungerstedt, U., Ljungberg, T., Hoffer, B., and Siggins, G. Dopaminergic supersensitivity in the striatum. In D. B. Calne, T. N. Chase, and A. Barbeau (Eds.), Advances in neurology, Vol. 9. Dopaminergic Mechanisms. New York: Raven Press, 1975, pp. 57–66.

    Google Scholar 

  • von Monakow, C. Diaschisis. (1914). Excerpted in K. H. Pribram (Ed.), Mood, States, and Mind. London: Penguin Books, 1969, pp. 27–37.

    Google Scholar 

  • Wall, P. D., and Egger, M. D. Formation of new connections in adult rat brains after partial deafferentation. Nature, 1971, 232, 542–545.

    Article  PubMed  Google Scholar 

  • Wall, P. D. Plasticity in the adult mammalian central nervous system. Unpublished manuscript, 1976.

    Google Scholar 

  • West, J. R., Deadwyler, S., Cotman, C. W., and Lynch, G. Time-dependent changes in commissural field potentials in the dentate gyrus following lesions of the entorhinal cortex in adult rats. Brain Research, 1975, 97, 215–233.

    Article  PubMed  Google Scholar 

  • Wickeigren, B. G., and Sterling, P. Influence of visual on receptive fields in cat superior colliculus. Journal of Neurophysiology, 1969, 32, 16–23.

    Google Scholar 

  • Will, B. E., and Rosenzweig, M. Effets de l’environnement sur la recuperation fonctionnelle après lesions cerebrales chez les rats adultes. Biology of Behaviour, 1976, 1, 5–16.

    Google Scholar 

  • Winans, S. S. Visual form discrimination after removal of the visual cortex in cats. Science, 1967, 158, 944.

    Article  PubMed  Google Scholar 

  • Zeki, S. M. The secondary visual areas of the monkey. Brain Research, 1969, 13, 197–226.

    Article  PubMed  Google Scholar 

  • Zigmond, J. J., and Stricker, E. M. Recovery of feeding after 6-hydroxydopamine (6-HDA) or lateral hypothalamic lesions: The role of catecholamines. Federation Proceedings of American Society for Experimental Biology, 1973, 32, 754.

    Google Scholar 

  • Zülch, K. J., Creutzfeldt, O., and Galbraith, G. C. Cerebral localization. Berlin: Springer-Verlag, 1975.

    Book  Google Scholar 

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  1. Department of Psychology, Clark University, Worcester, Massachusetts, 01610, USA

    Scott Laurence & Donald G. Stein

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  1. Washington University, St. Louis, Missouri, USA

    Stanley Finger

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Laurence, S., Stein, D.G. (1978). Recovery after Brain Damage and the Concept of Localization of Function. In: Finger, S. (eds) Recovery from Brain Damage. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7723-2_14

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