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Iron Metabolism pp 275–283Cite as

Anemia of Infection

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Abstract

Infections, particularly chronic infections, are frequently associated with anemia. Bacterial infections or conditions associated with severe sepsis may produce a fairly severe anemia of rapid onset, but the anemia of chronic disorders is usually not severe or progressive (Cartwright, 1966; Cartwright and Lee, 1971). In general, it is normochromic or slightly hypochromic, the PCV is seldom less than 30%, and the mean hemoglobin concentration of the red cells usually ranges between 28 and 32%. Hypochromia of the degree seen in iron-deficiency disease is unusual. Anisocytosis and poikilocytosis are not conspicuous, and signs of bone marrow regeneration such as polychromatophilia or the presence of nucleated red cells in the blood are absent. The number of reticulocytes is diminished or normal (Cartwright et al., 1946, 1951, 1954). An increased reticulocyte count is exceptional.

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  1. Iván Bernát M.D., D.Sc.
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© 1983 Akadémiai Kiadó, Budapest

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Bernát, I. (1983). Anemia of Infection. In: Iron Metabolism. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7308-1_19

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