Abstract
Single Photon Emission Computed Tomography (SPECT) has the capability of providing quantitative information about in-vivo radionuclide activity distribution using a rotating gamma camera, which is now available to most nuclear medicine departments. This quantitative potential has been limited largely because of the inability to accurately correct for the effects of photon attenuation. Researchers are becoming increasingly aware that knowledge of attenuation coefficients is necessary to implement accurate attenuation correction, particularly in the thorax. However, this normally necessitates an extra study. This paper proposes a method which overcomes this limitation by measuring the attenuation of the body with a transmission scan concurrent with the measurement of radiopharmaceutical distribution. The accuracy of the method when applied to iterative post-reconstruction attenuation correction is examined.
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References
Anger, H.O. and McRae, J. (1968). Transmission Scintiphotography, J.Nucl. Med. 9, 267–269.
Axelsson, B., Msaki, P. and Israelsson, A. (1984). Subtraction of Compton scattered photons in SPECT, J.Nucl.Med. 25, 490–494.
Bailey, D.L. (1986). Towards Quantitation in SPECT: A Dual Radionuclide Approach. M.App.Sc. thesis, NSWIT, Sydney.
Beck, R.N., Zimmer, L.T., Charleston, D.B. et al (1973). Advances in Fundamental Aspects of Imaging Systems & Techniques, in Medical Radionuclide Scintigraphy Vol I, pp 3–45, IAEA, Vienna.
Chang, L.T. (1978). A Method for Attenuation Correction in Radionuclide Computed Tomography, IEEE Trans.Nucl.Sci. NS-25, 638–643.
Filipow, L.J., Macey. D.J. and Munro, T.R. (1979). Measurement of the Depth of a Point Source of a Radioisotope from Gamma Ray Spectra, Phys.Med.Biol. 24, 341–352.
Hutton, B.F., Jayasinghe, M.A.C., Bailey, D.L. et al (1987). Artefact Reduction in Dual Radionuclide Subtraction Studies, Phys. Med. Biol. 32, 477–493.
Jayasinghe, M.A.C. (1984). Possibe improvements for the subtraction imaging technique in radio-imunodetection of cancer (RID), M.Sc. thesis, UNSW, Sydney.
Kuhl, D.E., Hale, J. and Eaton, W.L. (1966). Transmission Scanning: A Useful Adjunct to Conventional Emission Scanning for Accurately Keying Isotope Deposition to Radiographic Anatomy, Radiology 87, 278–284.
Larsson, S.A. (1980). Gamma Camera Emission Tomography, ACTA Radiologica Supplementum 363, pp24-30, Stockholm.
Malko, J.A., Van Heertum, R.L., Gullberg, G.T. et al (1986). SPECT Liver Imaging Using an Iterative Attenuation Correction Algorithm and an External Flood Source, J.Nucl.Med. 27, 701–705.
Manglos, S.H., Jaszczak, R.J., Floyd, C.E. et al (1987). Non-Isotropic Attenuation in SPECT: Phantom Tests of Quantitative Effects and Compensation Techniques, J.Nucl.Med. (in press).
Moore, S.C. (1982). Attenuation Compensation, in Computed Emission Tomography, Ell P.J. and Holman B.L.(Eds.), pp 339-360, Oxford University Press.
Moore, S.C., Brunelle, J.A. and Kirsch, C-M. (1982). Quantitative Multi-Detector Emission Computerized Tomography Using Iterative Attenuation Compensation, J.Nucl.Med. 23, 706 - 714.
Rutherford, R.A., Pullen, B.R., Goddard, J. et al (1975). Quantitative Information from the EMI scanner, in Information Processing in Scintigraphy, pp 353 - 376, Todd-Pokropek A. and Raynaud C.(Eds.), Orsay.
Sorenson, J.A., Briggs, R.C. and Cameron, J.R. (1969). 99m_ Tc Point Source for Transmission Scanning, J.Nucl.Med. 10, 252–253.
Tothill, P. and Galt, J.M. (1971). Quantitative Profile Scanning for the Measurement of Organ Radioactivity, Phys.Med.Bio1. 16, 625–634.
Walters, T.E., Simon, W., Chesler, D.A. et al (1981). Attenuation Correction in gamma emission tomography, J.Comput.Assist.Tomogr. 5, 89–94.
Webb, S., Flower, M.A., Ott, R.J. et al (1983). A comparison of attenuation correction methods for quantitative single photon emission computed tomography, Phys.Med.Biol. 28, 1045–1056.
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© 1988 Springer Science+Business Media New York
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Bailey, D.L., Hutton, B.F. (1988). Simultaneous Emission and Transmission Tomography. In: de Graaf, C.N., Viergever, M.A. (eds) Information Processing in Medical Imaging. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7263-3_38
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DOI: https://doi.org/10.1007/978-1-4615-7263-3_38
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