Abstract
It is a basic assumption that, for reasons unknown, the constituents of the human body may become antigenic, and then the patient produces antibodies against them. Some autoantibodies are tissue specific (e.g. haemolytic anaemia, pernicious anaemia) whereas others are non-tissue specific (e.g. systemic lupus erythematosus). To prove ‘autoimmunity’ in the strict sense is not an easy task. In any event, the outcome of antigenic stimulation—whether antibody formation or tolerance— seems to depend on the same factors for autoantigens as it does for any other antigen [146].
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Kelemen, E. (1975). Clinical Immunohaematological Physiopathology. In: Rajka, E., Korossy, S. (eds) Clinical Aspects of Immune Pathology. Immunological Aspects of Allergy and Allergic Diseases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7237-4_2
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