Transplantation Immunology

  • J. Wesley Alexander
Part of the Comprehensive Immunology book series (COMIMUN, volume 7)


It is appropriate that this important text concerning immunodermatology include a chapter devoted to transplantation since the skin has played such an important role in providing experimental models for studying transplantation immunobiology. Of much less importance currently is the role of skin allografting and xenografting in patient care. Even so, such grafts are used extensively as temporary biological dressings for cutaneous wounds, especially following burn injury.


Acute Rejection Graft Survival Skin Graft Chronic Rejection Mixed Lymphocyte Culture 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Alexander, J. W., and Good, R. A., 1977, Fundamentals of Clinical Immunology, Saunders, Philadelphia.Google Scholar
  2. Balch, C. M., and Marzoni, F. A., 1977, Skin transplantation during the pre-Reverdin era, 1804–1869, Surg. Gynecol. Obstet. 144: 766–773.PubMedGoogle Scholar
  3. Baldamus, C. A., McKenzie, I. F. C., Winn, H. J., and Russell, P. S., 1973, Acute destruction by humoral antibody of rat skin grafted to mice, J. Immunol. 110: 1532–1541.PubMedGoogle Scholar
  4. Balner, H., Cleton, F. L., and Eernisse, J. G. (eds.), 1965, Histocompatibility Testing, Munksgaard, Copenhagen.Google Scholar
  5. Barker, C. F., and Billingham, R. E., 1972, Analysis of local anatomic factors that influence the survival times of pure epidermal and full-thickness skin homografts in guinea pigs, Ann. Surg. 176: 597–604.PubMedCrossRefGoogle Scholar
  6. Baronio, G., 1804, Animal Grafts, Stamperia e Fonderia del Genio, Milan, Italy.Google Scholar
  7. Batchelor, J. R., and Hackett, M., 1970, HL-A matching in treatment of burned patients with skin allografts, Lancet 1970: 581–583.CrossRefGoogle Scholar
  8. Bert, P., 1863, Animal Grafts, Bailliere et Fils, Paris.Google Scholar
  9. Beni, P., 1865, Animal grafts, C. R. Acad. Sci. Ser. D 61: 587, 908.Google Scholar
  10. Brown, H. M., 1948, A motor driven dermatome, Ind. Med. 17: 46.Google Scholar
  11. Bunger, C., 1823, Successful case of a nose restoration from completely separated pieces of skin from the leg, J. Chir. Augen-Heilk. 5:562, translation in Plast. Reconstr. Surg. 44: 486 (1969).Google Scholar
  12. Burke, J. F., Quinby, W. C., Bondoc, C. C., Cosimi, A. B., Russell, P. S., and Szyfelbein, S. K., 1975, Immunosuppression and temporary skin transplantation in the treatment of massive third degree burns, Ann. Surg. 182 (3): 183–197.PubMedCrossRefGoogle Scholar
  13. Carpenter, C. B., d’Apice, A. J. F., and Abbas, A. K., 1976, The role of antibodies in the rejection and enhancement of organ allografts, Adv. Immunol. 22: 1–65.PubMedCrossRefGoogle Scholar
  14. Ceppellini, R., Curtoni, E. S., Mattiuz, P. L., LeighebGoogle Scholar
  15. G., Visetti, M., and Colombi, A., 1966, Survival of test skin grafts in man: Effect of genetic relationship and of blood group incompatibility, Ann. N.Y. Acad. Sci. 129: 421–445.Google Scholar
  16. Cooper, A., 1817, as quoted by C. M. Balch and F. A. Marzoni (1977).Google Scholar
  17. Dausset, J., and Rapaport, F. T., 1977, Immunology and genetics of transplantation, Perspect. Nephrol. Hyper-tens. 6: 97–138.Google Scholar
  18. Davies, D. A. L., and Staines, N. A., 1976, A cardinal role for I-region antigens (Ia) in immunological enhancement, and the clinical implications, Transplant. Rev. 30: 18–39.PubMedGoogle Scholar
  19. Davis, J. S., 1914, The use of small deep skin grafts, J. Am. Med. Assoc. 63: 985–989.CrossRefGoogle Scholar
  20. Dieffenbach, J. F., 1824, Transplantation of completely separated parts of the skin in a woman; and healing of the cheek that had been almost completely severed, J. Chir. Augen-Heilk. 6: 482.Google Scholar
  21. Eichwald, E. J., and Dolberg, M., 1977, Hyperacute rejection of murine skin grafts, Transplantation 23 (6): 516–521.PubMedCrossRefGoogle Scholar
  22. Girdner, J. L., 1881, Skin grafting with grafts taken from the dead subject, Med. Rec. N.Y. 20: 119.Google Scholar
  23. Jansen, J. L. J., Koene, R. A. P., v. Kamp, G. J., Hage-mann, J. F. H. M., and Wijdeveld, P. G. A. B., 1975, Hyperacute rejection and enhancement of mouse skin grafts by antibodies with a distinct specificity, J. Immunol. 115 (2): 392–394.PubMedGoogle Scholar
  24. Lafferty, K. J., and Woolnough, J., 1977, The origin and mechanism of the allograft reaction, Immunol. Rev. 35: 231–262.PubMedCrossRefGoogle Scholar
  25. Lafferty, K. J., Bootes, A., Dart, G., and Talmage, D. W., 1976, Effect of organ culture on the survival of thyroid allografts in mice, Transplantation 22 (2): 138–149.PubMedCrossRefGoogle Scholar
  26. Medawar, P. B., 1944, The behaviour and fate of skin autografts and skin homografts in rabbits, J. Anat. 78: 176–199.PubMedGoogle Scholar
  27. Medawar, P. B., 1945, A second study of the behaviour and fate of skin homografts in rabbits, J. Anat. 79: 157180.Google Scholar
  28. Nash, J. R., Peters, M., and Bell, P. R. F., 1977, Comparative survival of pancreatic islets, heart, kidney, and skin allografts in rats, with and without enhancement, Transplantation 24 (1): 70–73.PubMedCrossRefGoogle Scholar
  29. Nathan, P., Swartz, R., Jett, R., Jr., and MacMillan, B. G., 1971, A Comparison of Histocompatibility Typing and Mixed Lymphocyte Culture Tests in Burned Patients to Predict Survival of Skin Grafts (P. Matter, T. L. Barclay, and Z. Konickova, eds.), pp. 341–346, Hans Huber Publishers, Bern.Google Scholar
  30. Padgett, E. C., 1939, Calibrated intermediate skin grafts, Surg. Gynecol. Obstet. 69: 779–793.Google Scholar
  31. Pollock, G. D., 1871, Cases of skin-grafting and skin transplantation, Tr. Clin. Soc. Found. 4: 377.Google Scholar
  32. Reese, J. D., 1946, Dermatape: A new method for management of split skin grafts, Plast. Reconstr. Surg. 1: 98–105.CrossRefGoogle Scholar
  33. Reverdin, J. L., 1869, Epidermal grafts, Bull. Soc. Chir. Par. 10: 511.Google Scholar
  34. Rolley, R. T., Sterioff, S., Williams, C. M., and Parks, L. C., 1974, Assessment of immunocompetency by DNCB sensitization prior to human renal allotransplantation, Surg. Forum 25: 268–270.PubMedGoogle Scholar
  35. Rudolph, R., and Klein, L., 1973, Healing processes in skin grafts, Surg. Gynecol. Obstet. 136: 641–654.PubMedGoogle Scholar
  36. Smahel, J., 1977, The healing of skin grafts, Clin. Plast. Surg. 4 (3): 409–424.PubMedGoogle Scholar
  37. Tanner, J. C. Jr., Vandeput, J., and olley, J., F., 1964, Plast., Reconstr. Surg. 34 (3): 287–292.CrossRefGoogle Scholar
  38. Thiersch, 1874, Ueber die feineren anatomischen Veranderungen bei Aufheilung von Haut auf Granulationen, Arch. Klin. Chir. 17: 318–324.Google Scholar
  39. Thomas, F., Thomas, J., Mendez, G., Kirchoff, C., and Lee, H. M., 1977, Pretransplant monitoring of donor-recipient compatibility, Transplantation 24 (6): 442–448.PubMedCrossRefGoogle Scholar
  40. Warren, J. M., 1840, Taliacotian operation, Boston Med. Surg. J. 22: 261.CrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1981

Authors and Affiliations

  • J. Wesley Alexander
    • 1
    • 2
  1. 1.Department of SurgeryUniversity of Cincinnati College of MedicineCincinnatiUSA
  2. 2.Shriners Burns InstituteCincinnatiUSA

Personalised recommendations